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Completed

NCT Number: NCT04614090

Fast Reversal of Warfarin and Early Surgery in Patients With Trochanteric Hip Fracture A Case-control Study

A retrospective case-control study. To evaluate if early surgery within 24hours of troch or subtrochanteric hip fractures using intramedullary nailing is safe in patients on warfarin treatment after fast reversal of the warfarin effect

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Key information

Conditions

Trochanteric Hip Fractures Early Surgery Femoral Fractures Fractures, Bone Hip Fractures Hip Injuries Leg Injuries Warfarin Medication Wounds and Injuries

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Södersjukhuset

Stockholm, Sjukhusbacken 10, 11883, Sweden

Who can participate

Only the study team can determine whether someone qualifies for participation.

Exclusion criteria

  • Pathological fracture
  • Late presentation to the hospital
  • Other injuries

Treatment and study plan

Primary outcomes

  1. Transfusion rates

    Time frame: Pre-surgery

    Hb value (g/dl)

  2. Transfusion rates

    Time frame: Pre-surgery

    Transfusion rate (n)

  3. Transfusion rates

    Time frame: During the surgery

    Hb value (g/dl)

  4. Transfusion rates

    Time frame: During the surgery

    Transfusion rate (n)

  5. Transfusion rates

    Time frame: 2-4 days after the surgery

    Hb value (g/dl)

  6. Transfusion rates

    Time frame: 2-4 days after the surgery

    Transfusion rate (n)

  7. adverse events

    Time frame: Immediately after the surgery

    Number of patients with a myocardial infarction, stroke, pulmonary embolism, deep venous thrombosis, sepsis, pneumonia, urinary tract infection, pressure ulcer, or any adverse events.

  8. mortality

    Time frame: Immediately after the surgery

    The number of deaths

  9. mortality

    Time frame: 30-days after the surgery

    The number of deaths

  10. mortality

    Time frame: 1 year after the surgery

    The number of deaths

Sponsors and collaborators

Lead sponsor

Karolinska Institutet

Other

Collaborators

  • Stockholm South General Hospital

Registry information

Official study title

Is Fast Reversal and Early Surgery (Within 24 h) in Patients on Warfarin Medication With Trochanteric Hip Fractures Safe: A Case-control Study

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Nov 3, 2020
Registry last updated
Nov 3, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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