Factors Associated With Mortality in Streptococcal Anginosus Bacteremia

Streptococcal anginosus infections (S. constellatus, S. anginosus, and S. intermedius) are characterized by their severity, linked to high mortality and frequent infectious complications. Several studies in the literature highlight this severity, with mortality rates estimated at around 15%.

The aim of this research is to identify the factors associated with mortality in Streptococcal anginosus bacteremia.

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Key information

Conditions

Streptococcal Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre de référence des maladies vectorielles à tiques, CNR Borrelia - CHU de Strasbourg - France

Strasbourg, 67091, France

Location status: Recruiting

Location contact

Morgan JAMOT-DUBOIS, MD

PRINCIPAL_INVESTIGATOR

Victor GERBER, MD

PRINCIPAL_INVESTIGATOR

Victor Gerber, MD

CONTACT

[email protected]

33 3 68 85 37 97

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Major subject (≥18 years old)
Hospitalized between January 1, 2019, and December 31, 2024, in one of the participating centers
Having presented during the study period at least one positive blood culture for Streptococcus anginosus, Streptococcus constellatus, or Streptococcus intermedius in a laboratory at a participating center

Exclusion criteria

Refusal to participate in the study

Treatment and study plan

Primary outcomes

28-day in-hospital mortality

Time frame: 28-Day Mortality Following Streptococcal Infection

28-Day In-Hospital Mortality Following Streptococcal Infection

Study contacts

Contact information is provided by the study sponsor or research team.

Victor GERBER, MD

CONTACT

[email protected]

33 3 68 85 37 97

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: SGA

Important dates

Study start: 2025
Primary completion: 2027
Study completion: 2027
First posted: Jan 15, 2026
Registry last updated: Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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