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OpenTrials
Completed

NCT Number: NCT05667233

Examining Changes in Muscle Size and Body Composition Between Two Hypertrophy Resistance Training Programs in Males

This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.

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Key information

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Dalplex Fitness Centre

Halifax, Nova Scotia, B3H 4R2, Canada

About this study

Resistance training is commonly used to improve body composition, gain strength, increase muscle size (i.e., hypertrophy) and prevent muscle atrophy (i.e., muscle wasting). The most optimal mode of building muscle remains unclear, however there are many mechanisms that can be tested to yield optimal results. One variable that can be manipulated when designing a hypertrophy-focused resistance training regimen is intensity (i.e., proximity-to-failure). Proximity-to-failure is defined as the number of repetitions remaining in a set of prescribed exercises prior to reaching momentary muscular failure (MMF). MMF is when an individual cannot complete the lowering or concentric phase of a given repetition with a full range-of-motion without deviation from the prescribed form of the exercise. For all lifters, particularly amongst older populations, it can be psychologically demanding to push to MMF, and may increase the risk of delayed onset muscle soreness (DOMS) and/or injury due to technical breakdown. In contrast, there is some evidence that suggests training to a slightly less intensity (i.e., within 1-4 repetitions in reserve [RIR]) may result in comparable hypertrophic results with less of a physical and psychological demand on participants.

For these reasons, this study looks to investigate if an easier (i.e., less intense) approach to training such as training with repetitions in reserve (RIR), warrants similar or better muscle hypertrophy adaptations to MMF.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • biological male
  • age 18 years or older
  • enrolled at Dalhousie university
  • minimum 3-months of consistent (at least 2x/week) resistance training experience

Exclusion criteria

  • body fat percentage 25% or greater (obese)
  • use of performance enhancing drugs that aim to increase rate of muscle growth (i.e., androgenic steroids, anabolic steroids, selective androgen receptive modulators, growth hormone).

Treatment and study plan

Resistance Training Program

Other

Participants will undergo a high exertion machine-based resistance training protocol.

Primary outcomes

  1. Segment girth (cm)

    Time frame: 8-weeks

    Upper arm (biceps) circumference, mid-thigh (quadriceps) circumference, waist (abdomen) circumference

Secondary outcomes

  1. Body composition (kg)

    Time frame: 8-weeks

    Fat mass, Fat-free mass, Total Body Mass (fat mass + fat free mass)

  2. Body Fat Percentage

    Time frame: 8-weeks

    Fat Mass (kg) / Total Body mass (kg) * 100

Sponsors and collaborators

Lead sponsor

Dalhousie University

Other

Registry information

Official study title

A Pilot Study Examining Differences in Waist, Upper-arm, Mid-thigh Circumference and Body Composition When Training to Momentary Muscular Fatigue Versus Close Failure-proximity Amongst Healthy Male Biological Sex University-aged Students

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Dec 28, 2022
Registry last updated
Aug 15, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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