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Completed

NCT Number: NCT05952193

Evaluation of the POSOS Device for Iatrogenesis Detection in Clinical History? A Vignettes Study

This study is a multicenter evaluation of diagnostic performance using simulated clinical vignettes. It aims to test the effectiveness of the POSOS app in detecting drug-induced iatrogenesis in urgent medical situations, an issue of public health importance. Participating physicians, who are randomly assigned to either use or not use POSOS, are categorized based on their years of experience. Vignettes, including a mixture of complex, simple, and non-iatrogenesis cases, are assigned to these doctors. During the simulation, physicians respond to their respective vignettes on the YgheniVi platform, with responses recorded at two intervals (5 min and 15 min). The supervising physicians subsequently fill out an e-CRF, providing further data on the time spent, the number of medical research applications used, and the overall user experience of POSOS. A doctor/pharmacist pair then corrects the answers to the vignettes.

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Key information

Conditions

Iatrogenesis Artificial Intelligence Clinical Vignettes Diagnostic Performance Study Medical Information Search

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens

Amiens, 80480, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Not applicable as the study population is made up of clinical vignettes, there is no inclusion of patients.
  • The physicians included are emergency physicians, selected by convenience so as to have as many physicians (seniority of practice 3 years after thesis) as (seniority of practice less).

Exclusion criteria

  • Not applicable.
  • Simulations with technical faults will be excluded: (absence of the test doctor, internet access not working, PC malfunction, serious disruptions during the simulation).

Treatment and study plan

Primary outcomes

  1. the proportion of overall correct responses in each groups

    Time frame: 5 minutes

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Collaborators

  • CHU de Créteil
  • CHU de Reims
  • CHU de Rouen - Accueil
  • Centre Hospitalier Régional Metz-Thionville
  • Centre Hospitalier Universitaire de Nice
  • Centre Hospitalier de Bourg en Bresse
  • Centre Hospitalier de Niort
  • Médipôle Lyon-Villeurbanne
  • Saint Antoine University Hospital
  • University Hospital, Grenoble
  • University Hospital, Lille
  • University Hospital, Montpellier

Registry information

Acronym: YGenHiVi

Important dates

Study start
2023
Primary completion
2023
Study completion
2025
First posted
Jul 19, 2023
Registry last updated
Jun 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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