Evaluation of the Efficacy of Permanent Course Combined Therapy With CYTOFLAVIN® Intravenous Solution and CYTOFLAVIN Tablets, at 2-3 Stages of Rehabilitation of Patients With Post Intensive Care Syndrome

Inclusion criteria

• Men and women over 18 years of age and older;
• Stay in the ITU and (or) intensive care unit for at least 3 days;
• Diagnosed "post intensive care" syndrome (PIC syndrome) with moderate-to-severe severity >3<6 points
• Diagnosed modalities "critical illness polyneuropathy, respiratory neuropathy, dysphagia" of the domain "Neuromuscular complications" of PIC syndrome at 2-3 stages of the rehabilitation route at any value of PICS severity index
• Diagnosed modalities "decreased gravitational gradient, decreased exercise tolerance" in the domain "Vegetative-metabolic complications" at 2-3 stages of the rehabilitation route at any value of PICS severity index

Exclusion criteria

• Premorbid level of vital activity when assessed on the rehabilitation routing scale 4-5 points;
• Hematocrit ≤30%;
• Hemoglobin level ≤80 g/L;
• Acute cardiac failure;
• Acute respiratory failure;
• Acute renal failure;
• Acute liver cell failure;
• Use of drugs from "metabolic agents" pharmacotherapeutic group at the time of inclusion in the study
• Life expectancy of 6 months or less or presence of incurable diseases in decompensation stage