Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct

Inclusion criteria

• Age ≥18 years, men or women.
• Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA/MRA/DSA.
• Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days.
• Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.

Exclusion criteria

• Subjects with occlusions in both anterior and posterior circulation.
• CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed).
• Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset/last known well time, or missing major treatment information including whether EVT was performed).
• Baseline NIHSS score <6.
• Woman of childbearing potential who is known to be pregnant or lactating or who has a positive pregnancy test on admission.
• Missing follow-up outcomes at 90 days.
• Any other condition judged by investigators to substantially affect analysis or interpretation.