Evaluation of the Efficacy of Panax Ginseng on Lipid Metabolism in Men and the Relationship With Sports Practice.

Panax Ginseng (P ginseng), C.A. Meyer, Red, Chinese or Korean ginseng is a plant from eastern Asia and is one of the most widely used herbal products in the world. P ginseng has been been used for many years for different medical therapies. Previous studies have demonstrate that P. ginseng root extract supplementation may promote fat oxidation, increase hepatic glycogen levels and produce a glycogen-sparing and antifatigue effect during exercise in swimming rats. Notwithstanding, although there is some evidence of P. ginseng effects in humans, no evidence has been obtained respect to its supplementation in human sport performance. The aim of this study is to assess the effect of P ginseng extract supplementation on the lipid metabolism and sport performance in male endurance runners. For this purpose, the effect of supplementation for 2 weeks of 500 mg/day of P. ginseng will be evaluated in a sub-maximal physical stress test. Variables of lipid metabolism, energy consumption, fatigue, and endurance will be determined.

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Key information

Conditions

Sports Physical Therapy

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Early Phase 1

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Athletic men of aerobic type, who participate in a supervised training as a previous step to the accomplishment of competitions
Which their age is older than 18 years
Training superior or equal to 3 days per week and that these workouts are stable during the intervention.

Exclusion criteria

Athletes with high blood pressure, with pharmacological treatment for hypercholesterolemia, diabetes, any psychiatric illness
Athletes who practice sports without having the objective of increasing sports performance
Athletes who use some type of ergogenic sport supplementation looking to optimize any aspect related to the sport.

Treatment and study plan

Panax Ginseng Supplementation

Dietary Supplement

500 mg/day of Panax Ginseng

Placebo supplementation

Dietary Supplement

500 mg/day of Cellulose

Primary outcomes

Change from baseline plasmatic Total Lipids at 2 weeks

Time frame: 2 weeks

Total Lipids in the plasma are measured in mg / dL
Change from baseline plasmatic Triglycerides at 2 weeks

Time frame: 2 weeks

Triglycerides in the plasma are measured in mg / dL
Change from baseline Respiratory Exchange Rate at 2 weeks

Time frame: 2 weeks

To quantify the amount of Oxygen consumed and the amount of carbon dioxide produced. (mL/Kg/Min)

Sponsors and collaborators

Lead sponsor

Universitat de Lleida

Other

Registry information

Acronym: GinsengRun

Important dates

Study start: 2016
Primary completion: 2018
Study completion: 2019
First posted: Mar 25, 2019
Registry last updated: May 2, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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