Evaluation of the Circulatory Status of Stomach Tube and Gastrooesophageal Anastomosis

The incidence of anastomotic leaks after gastroesophageal anastomosis after thoracolaparoscopic cancer esophagus surgery is high at the Oslo University Hospital. The patients selected for operation shall be investigated for microcirculatory changes at the thoracic anastomosis site and followed up for any post operative anastomotic leaks.

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Key information

Conditions

Circulatory; Change Microcirculation

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of vascular surgery, Oslo University Hospital, Oslo, Norway

About this study

Microcirculation shall be evaluated during the operation with trans serosal laser doppler flowmetry and visible light spectroscopy (LDFVLS). Different anatomical areas of the stomach and gastric tube shall be examined With LDFVLS to find any changes in SO2, rHb, flow, and velocity. Repeat measurements shall be taken to compare them with the baseline measurements.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with oesophageal carcinoma planned to have thoracolaparoscopic operation and thoracic gastroesophageal anastomosis shall be included.

Exclusion criteria

Patients who do not give written consent will not be included.

Treatment and study plan

Primary outcomes

Impact of local microcirculatory changes on the thoracooesophegial anastomosis after cancer oesophagus surgery

Time frame: 6 months

Repeated measurements of microcirculation With laser dopper flometer and visible light spectrometry shall be performed trans serosally of the stoach and gastric tube to register changes in microcirculation. Patients shall be followed up for anastomotic leaks. Besides CT angiography shall be performed before surgery.

Sponsors and collaborators

Lead sponsor

Oslo University Hospital

Other

Registry information

Official study title

Impact of Circulatory Changes on Thoracic Anastomosis in Patients Undergoing Thoracolaparoscopic Surgery for Oesophageal Carcinoma

Important dates

Study start: 2018
Primary completion: 2020
Study completion: 2020
First posted: Oct 30, 2018
Registry last updated: Oct 6, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed