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NCT Number: NCT06559566

Evaluation of Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery

Ultrasonography(USG)-guided optic nerve sheath diameter measurement and its correlation with brain computed tomography in the evaluation of intracranial pressure in patients who underwent intracranial brain tumor surgery.

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Key information

About this study

Optic Nerve Sheath Diameter (ONSD) Measurement is a non-invasive diagnostic method used to detect increased intracranial pressure, and in general, ONSD measurement over 5 mm has been found to be associated with increased intracranial pressure.ONSD will be measured using an USG device within the specified time periods.

T0: Before anesthesia induction T1: First 5 minutes immediately after induction of anesthesia T2: At the end of the surgery before extubation /minute T3: Within the first hour/minute after extubation T4: 12 hours/minute after tumor resection T5. 24 hours/minute after tumor resection

ONSD measurement in brain computer tomography (BCT); Eyeball diameter and optic nerve diameter measurements will be made on BCT transverse images at the optic nerve level and recorded.In patients, USG and BCT correlation comparison is planned before the operation (T0), in the first hour after the end of post-operative surgery (T3) and at the 24th hour after post-operative surgery (T5).

T0: ONSD measurement in pre-operative Brain CT T3: BCT ONSD measurement/minute within the first hour following the postoperative period T5: BCT ONSD measurement/minute 24 hours following the postoperative period

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 -65 years
  • Brain malignant neoplasm tumor
  • Brain benign neoplasm supratentorial
  • Brain benign neoplasm infratentorial information

Exclusion criteria

  • Patients who cannot provide adequate image quality in ocular ultrasonography
  • Who are unconscious or have a Glasgow coma scale of less than 15
  • Pseudotumor cerebri
  • Optic nerve arachnoid cyst
  • Patients with open injuries involving the eyelid and surrounding area
  • Optic nerve malignant neoplasm
  • Injury of the optic nerve and its pathways
  • Systemic Lupus Erythematosis,
  • Scleroderma
  • Multiple Sclerosis, sarcoidosis
  • Thyrotoxicosis (hyperthyroidism)

Treatment and study plan

USG

Procedure

The aim of this study is to measure the intracranial pressure of patients planned for brain tumor surgery by measuring the optic nerve sheath diameter (ONSD) under USG guidance and compare its correlation with the computed brain tomography.

Other names: ONSD measurement with USG

BCT

Procedure

The aim of this study is to measure the intracranial pressure of patients planned for brain tumor surgery by measuring the optic nerve sheath diameter (ONSD) under USG guidance and compare its correlation with the computed brain tomography.

Other names: ONSD measurement with BCT

Primary outcomes

  1. intracranial pressure

    Time frame: T0: Before anesthesia induction T1: peroperative5. minutes T2: At the end of the surgery 6.hours T3:after extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours

    To compare the optic nerve diameter measurement ,USG and BBT values used to measure intracranial pressure in patients with brain tumor surgery

Secondary outcomes

  1. Heart Rate

    Time frame: T0: Before anesthesia induction T1: preoperative 5.minutes T2: At the end of the surgery 6.hoursT3:after extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours

    To compare the heart rate measurement

  2. Blood pressure

    Time frame: T0: Before anesthesia induction T1: preoperative 5.minutes T2: At the end of the surgery 6.hours T3 extubation 1 hours T4: postoperative 12.hours T5. postoperative 24.hours

    To compare the blood pressure measurement

Study contacts

Contact information is provided by the study sponsor or research team.

SEZEN KUMAS SOLAK, MD

CONTACT

[email protected]

+905055729494

Sponsors and collaborators

Lead sponsor

Sezen Kumaş Solak

Other Gov

Collaborators

  • Bagcilar Training and Research Hospital

Registry information

Official study title

Comparison of Two Methods Used to Asses Postoperative Intracranial Pressure in Patients Undergoing Intracranial Tumor Surgery

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 19, 2024
Registry last updated
Aug 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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