Evaluation of Patients With Known or Suspected Heart Disease

In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).

Patients participating in this study will undergo a general medical evaluation, including blood tests, urine, examination, chest x-ray and electrocardiogram (EKG). In addition, patients may be asked to have an echocardiogram (ultrasound scan of the heart) and to perform an exercise stress test.

These tests are designed to assess the types and causes of patient's heart diseases and to determine if they can participate in other, specific research studies.

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Key information

Conditions

Peripheral Artery Disease Angina Pectoris Aortic Stenosis, Subvalvular Aortic Valve Disease Aortic Valve Stenosis Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Cardiomegaly Cardiomyopathies Cardiomyopathy, Dilated Cardiomyopathy, Hypertrophic Cardiovascular Diseases Chest Pain Congenital, Hereditary, and Neonatal Diseases and Abnormalities Coronary Artery Disease Coronary Disease Diabetes Mellitus Diabetes and Heart Failure Dilated Cardiomyopathy Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genetic Diseases, Inborn Glucose Metabolism Disorders Heart Diseases Heart Failure Heart Valve Diseases Hypertension Hypertension, Pulmonary Kidney Diseases Laminopathies Lung Diseases Male Urogenital Diseases Metabolic Diseases Microvascular Angina Myocardial Ischemia Neurologic Manifestations Nutritional and Metabolic Diseases Pain Pathological Conditions, Signs and Symptoms Peripheral Arterial Disease Peripheral Vascular Diseases Pulmonary Hypertension Renal Artery Obstruction Renal Artery Stenosis Respiratory Tract Diseases Signs and Symptoms Urogenital Diseases Urologic Diseases Vascular Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

About this study

The principal mission of the NIH is the conduct of research that elucidates biological mechanisms, pathogenesis, and treatment of disease. Patients with known or suspected cardiovascular diseases are referred to NHLBI cardiologists for consideration of participation in clinical research protocols. However, eligibility for participation is often uncertain from referral information or even after an outpatient evaluation. The purpose of this protocol is to permit inpatient evaluation of patients for whom participation in clinical research protocols is under consideration in order to determine protocol eligibility by means of conventional laboratory and cardiovascular testing.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

INCLUSION CRITERIA:

The following is a representative list of the types of patient presentations and potential diagnoses eligible for this protocol:

Coronary artery disease with angina or inducible myocardial ischemia as determined by noninvasive testing.
Cardiomyopathies including congestive phenotypes.
Peripheral artery disease with intermittent claudication or limb-threatening ischemia.
Renovascular disease with uncontrolled hypertension, intermittent pulmonary edema, or evidence of ischemic nephropathy.
Upper extremity peripheral artery disease.
Diabetes with heart failure.
Pulmonary hypertension.

Exclusion criteria

Pregnancy, for those patients who require catheterization-based diagnostics.

Inability to provide informed consent.

Sponsors and collaborators

Lead sponsor

National Heart, Lung, and Blood Institute (NHLBI)

Nih

Registry information

Official study title

Evaluation of Patients With Known or Suspected Heart Disease (Screening Protocol)

Important dates

Study start: 1992
Study completion: 2009
First posted: Nov 4, 1999
Registry last updated: Jul 2, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed