Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Pupil light reflex (PLR) will be measured by a chromatic multifocal pupillometer in response to short and long wavelength light with small spot stimulus in 76 points of the 30 degree visual field.

A computerized infrared video pupillometer will be used to record changes in pupil diameter in response to short- and long-wavelength stimuli (peak 485 nm and 620 nm, respectively) presented by 76 LEDs, 1.8mm spot size, at light intensities of 10-3000 cd/m2 and duration of 1-3 sec at different points of the 30 degree visual field

Inclusion criteria

• Age 18-80 years old.
• Signing informed consent.
• Pupillary reflex to light.

Exclusion criteria

• Cloudy corneas.
• Surgical intraocular ophthalmic procedure within the past 30 days.
• No reactive pupils.
• Synechia of the iris to the lens after surgery or inflammation.
• Neovascularization.
• Axenfeld-Rieger Syndrome.
• Iris atrophy (ICE syndrome).
• Iris coloboma.
• Sphincter damage due to ischemia.
• Sphincter damage due to trauma (tears of sphincter or diffuse damage to muscle).
• Sphincter damage due to Herpes Zoster Uveitis.
• Sphincter damage due to high intraocular pressure.
• Iris tumor or cyst.
• Ectropion uvae.
• Adie's pupil.
• Third nerve aberrant regeneration of the iris sphincter.
• RP patients with Optic neuropathy with the potential of producing a positive RAPD (Relative Afferent Pupillary Defect).
• Chronic use of myotics or mydriatics.
• Systemic medication that have affect on pupillary reflex .
• Any condition preventing accurate measurement or examination of the pupil.