Evaluation of Obex® in Overweight and Obesity

Inclusion criteria

• Patients who fulfill the diagnosis criteria of overweight or obesity (BMI ≥ 25.0 and less than 40).
• Age between 20 and 65 years old.
• Values of fasting glucose < 7.0 mmol / L and at two hours < 11.1 mmol / L during Glucose Tolerance Test (OGTT).
• Written informed consent of participation in the study.

Exclusion criteria

• Thyroid dysfunction (hypo or hyperthyroidism).
• Type 1 or type 2 diabetes.
• Prediabetes treated with oral agents.
• Alterations of lipids treated with drugs.
• Medicine consumption of or dietary supplements that influence the reduction of body weight.
• Consumption of steroids or prolonged use of them (last 3 months).
• Treatment with immunosuppressive drugs.
• Chronic diseases (of the hepatic, renal and cardiovascular systems, pancreatitis or some type of malignancy condition) or acute at the time of inclusion.
• Insulin resistance due to diseases such as acromegaly, endogenous hypercortisolism, polycystic ovarian syndrome or hyperprolactinemia.
• History of symptomatic hypoglycaemia.
• History of chronic debilitating diseases, anemia and collagen diseases.
• History or existence psychological illness with eating disorders or toxicity.
• History of alcoholism or drug dependence.
• Inability to comply with the instructions of the investigation.
• Severe infections at the time of inclusion.
• Women of childbearing age who use hormonal contraceptives (oral or injectable).
• Pregnant or breastfeeding.
• Known sensitivity to any of the components of the formulation
• Gynoid fat distribution.