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OpenTrials
Completed

NCT Number: NCT05763173

Evaluation of Lung Metastases Based on Ultrashort Echo Time MRI

Analyze the diagnostic efficiency (including performance, diameter, and location of nodules) of UTE-MRI in lung metastases of hepatoblastoma with chest CT as gold standard

Completed

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Key information

Age range

Up to 14 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, Shanghai Municipality, 200127, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children diagnosed as hepatoblastoma (including treated with neoadjuvant chemotherapy but not surgery)
  • Recent chest CT scan (within 14 days)
  • No MRI contraindications
  • The guardian of the children are willing to undergo the examination after full communication and informed consent

Exclusion criteria

  • MRI contraindications (including but not limited to: contrast medium allergy; Claustrophobia;Metal implants;chronic kidney disease≥stage 3 (glomerular filtration rate < 60 mL min-1 (1.73 m2)-1))
  • Patients with hepatoblastoma aged 14 years and above
  • Children after surgery for hepatoblastoma
  • Application of any contrast medium within 24 h before the MRI and/or CT examinations
  • There is a concomitant medical condition (e.g. poorly controlled hypertension, severe diabetes, neurological or psychiatric illness, etc.) or any other condition that would seriously endangers the subject's safety, may confuse the study results, or may interfere with the subject's completion of the study according to the investigator's judgment.

Treatment and study plan

Primary outcomes

  1. UTE-MRI assessment of lung metastases with chest CT as gold standard

    Time frame: Baseline to 14 days

    Analyze the diagnostic efficiency (including performance, diameter, and location of nodules) of UTE-MRI in lung metastases of hepatoblastoma.

Sponsors and collaborators

Lead sponsor

RenJi Hospital

Other

Registry information

Official study title

The Diagnostic Value of Lung Ultrashort Echo Time MRI for Potential Lung Metastases in Children With Hepatoblastoma

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Mar 10, 2023
Registry last updated
Apr 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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