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Completed

NCT Number: NCT02777346

Evaluation of Emergency Suturing With Absorbable Versus Non-absorbable Suture Material in a Pediatric Population

The investigators recruit patients admitted to the Pediatric Emergency Department of the Geneva's University Hospital with open wounds needing suture. The patients are treated with absorbable versus non-absorbable suture material according to randomization.

Outcomes are:

1. infection rate at the first follow-up (between 4 and 14 days, depending on the sutured site and defined by protocol) 2. scar appearance at a 6-months follow-up.

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Key information

Age range

1 day–16 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Geneva University Hospital

Geneva, Canton of Geneva, 1205, Switzerland

About this study

The investigators recruit patients admitted to the Pediatric Emergency Department of the Geneva's University Hospital with open wounds needing suture. The patients are treated with absorbable versus non-absorbable suture material according to randomization.

After obtaining the patient's/parent's consent and randomization, the suture material will be provided.

Selection of the size of the thread and the date of the first follow-up are determined as follows:

  • Face: Thread size 5-0 to 7-0, first follow-up 4-7 days
  • Torso/back: Thread size 4-0 or 5-0, first follow-up 10-14 days
  • Arms: Thread size 4-0 or 5-0, first follow-up 7- 10 days
  • Hand: Thread size 5-0 or 6-0, first follow-up 7-10 days
  • Legs: Thread size 4-0 or 5-0, first follow-up 7-14 days

The patients are examined by in the outpatient wound clinic by specialised nurses under medical supervision at the first follow-up, and at six months by one of the investigators.

Outcomes:

  • infection rate at the first follow-up (between 4 and 14 days, depending on the sutured site and defined by protocol)
  • scar appearance at a 6-months follow-up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient younger than 16 years of age with a wound requiring suture

Exclusion criteria

  • Deep wounds with lesions of subcutaneous structures (tendons, nerves, etc.)
  • Wounds with tissue loss
  • Diabetic patients or patients treated with drugs potentially compromising cicatrization (e.g. steroids, immunosuppressors, etc.)
  • Wounds caused by animal or human bites
  • Sutures not performed in the emergency room
  • Heavily soiled wounds

Treatment and study plan

Absorbable

Device

Wound suture by a resident physician. Two follow-up appointments (first at 4 to 21 days after the suture, according to the sutured site as defined by protocol, second at 6 months) Standardized photography of the wound before the suture and at the two subsequent follow-ups.

Evaluation of the scar with a standardised form by a specialised nurse under medical supervision at the first follow-up and by a panel of investigators at 6 months using the pictures taken at the follow-up appointments.

Non absorbable

Device

Wound suture by a resident physician. Two follow-up appointments (first at 4 to 21 days after the suture, according to the sutured site as defined by protocol, second at 6 months) Standardized photography of the wound before the suture and at the two subsequent follow-ups.

Evaluation of the scar with a standardised form by a specialised nurse under medical supervision at the first follow-up and by a panel of investigators at 6 months using the pictures taken at the follow-up appointments.

Primary outcomes

  1. Short-term infection risk

    Time frame: 4 to 21 days

    Scars classified as "no evidence of infection", "signs of inflammation" and "signs of active infection"

Secondary outcomes

  1. Scar appearance

    Time frame: 6 months

    Scoring based on the Manchester scar scale

Sponsors and collaborators

Lead sponsor

Pediatric Clinical Research Platform

Other

Registry information

Important dates

Study start
2016
Primary completion
2025
Study completion
2025
First posted
May 19, 2016
Registry last updated
Jul 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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