Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT07459374

Evaluating Universal Adhesives in Cervical Lesions

The aim of this randomized controlled clinical trial is to evaluate the 12-month clinical performance of restorations placed in NCCLs using universal adhesives with different compositions according to FDI criteria.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hacettepe University

Ankara, 06100, Turkey (Türkiye)

About this study

This controlled, randomized, single-blind clinical trial will compare the clinical effectiveness of three universal adhesive systems with different compositions in the restoration of non-carious cervical lesions. A total of 30 healthy volunteers aged 18-55 years will be included. Each participant must present with at least three vital posterior teeth with non-carious cervical lesions (≥3 lesions), with both enamel and dentin involvement and with antagonist teeth in occlusion. Each participant will receive restorations using all three adhesive systems in different teeth (split- mouth design). Randomization will be performed using a computer-generated randomization table (Research Randomizer Program). An experienced operator from the Department of Restorative Dentistry will perform all restorative procedures (AUT). Radiographs will be taken at baseline (before treatment) and at 12-, 24- and 36-month follow-up appointments to assess adaptation, marginal integrity, and proximity to the pulp. Additional radiographs will only be taken if clinically indicated (e.g., suspected endodontic involvement). Restorations will be evaluated immediately after placement, at 12-, 24- and 36-month using FDI evaluation criteria.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals aged 18-55 years
  • No systemic condition contraindicating restorative treatment
  • Brushing teeth at least twice daily
  • At least 20 teeth in occlusion
  • At least three vital posterior teeth with non-carious cervical lesions and antagonist teeth
  • Completed initial periodontal therapy
  • Signed informed consent

Exclusion criteria

  • Healthy individuals aged 18-55 years
  • No systemic condition contraindicating restorative treatment
  • Brushing teeth at least twice daily
  • At least 20 teeth in occlusion
  • At least three vital posterior teeth with non-carious cervical lesions and antagonist teeth
  • Completed initial periodontal therapy
  • Signed informed consent

Treatment and study plan

G2 Bond Universal, GC Europe N.V., Leuven, Belgium

Device

G2 Bond Universal, GC Europe N.V., Leuven, Belgium

Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA

Device

Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA

Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan

Device

Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan

Primary outcomes

  1. Restoration survival rate at 12 months

    Time frame: From baseline to 12 month

    Restoration survival rate at 12 months, defined as:

    At least 90% of restorations remaining in situ No statistically significant difference among groups according to FDI criteria

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Official study title

Evaluation of the Clinical Performance of Universal Adhesives in Non-Carious Cervical Lesions: A Randomized Controlled Clinical Trial

Important dates

Study start
2024
Primary completion
2025
Study completion
2028
First posted
Mar 9, 2026
Registry last updated
Mar 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.