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NCT Number: NCT07549334

Evaluating the Use of Prehospital Lung Ultrasound in EMS: A Multicenter Pilot Study

The goal of this prospective nonrandomized study is to determine if prehospital lung ultrasound findings result in a change in patient management. This study will look at how lung ultrasound exam improves diagnosis of respiratory distress in patients being treated by Emergency Medical Services, such as patients with heart failure. Additional questions include:

* How well can paramedics obtain and interpret ultrasound images? * How does ultrasound use change treatment received by patients? * How does ultrasound use impact patient outcomes? Participants will receive a lung ultrasound exam, but otherwise receive standard evaluation and care. Patients who receive ultrasound will be compared to those who did not receive ultrasound for logistical reasons and patients from before the use of ultrasound. Ultrasound will not be withheld from any patient for the purposes of the study.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Christiana Care/New Castle County EMS, Newark, Delaware, United States

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient treated by Emergency Medical Services
  • Complaint of dyspnea

At least one of the following:

  • Oxygen saturation <94% on room air
  • Abnormal lung sounds
  • Increased work of breathing
  • Pedal edema
  • Orthopnea

Exclusion criteria

  • Pediatric patients (<18)
  • Traumatic etiology
  • Cardiac arrest at any point prehospitally
  • No ultrasound-trained paramedic involved in patient's care

Treatment and study plan

Pulmonary ultrasound

Diagnostic Test

Ultrasound of up to six lung zones (1, 2, and 4) will be obtained. Paramedics will assess for the presence of B lines.

Primary outcomes

  1. Frequency with which prehospital lung ultrasound findings result in a change in patient management by EMS

    Time frame: From time of patient encounter to patient handoff at the hospital. (anticipated average of one hour)

    Frequency of management changes will be compared from before prehospital ultrasound was used to after prehospital ultrasound has been implemented.

Secondary outcomes

  1. Survival to discharge

    Time frame: At time of hospital discharge (anticipated average one week)

  2. Percent of prehospital diagnoses agreeing with hospital diagnosis

    Time frame: At time of hospital discharge (anticipated average of one week)

    Diagnostic accuracy

  3. Whether or not patient is intubated by EMS or during hospital admission, recorded as yes or no

    Time frame: EMS patient encounter to hospital discharge (anticipated average one week)

  4. Days on ventilator or non-invasive ventilation

    Time frame: Hospital arrival to hospital discharge (anticipated average one week)

  5. Length of stay

    Time frame: Hospital arrival to hospital discharge (anticipated average one week)

  6. Length of ICU stay

    Time frame: Hospital admission to hospital discharge (anticipated average one week)

  7. Paramedic ultrasound interpretation accuracy

    Time frame: Enrollment

    Comparison between paramedic interpretation (of presence of lung sliding and number of B lines) with physician interpretation

  8. Quality of ultrasound obtained by paramedic

    Time frame: Enrollment

    Rating of ultrasound using a five-point scale (1 being no recognizable structures, 5 being criteria met for diagnosis, all structures imaged with excellent image quality and diagnosis completely supported) by physician

Study contacts

Contact information is provided by the study sponsor or research team.

Andrew Grandin

CONTACT

[email protected]

6099006518

Elizabeth Blizzard

CONTACT

[email protected]

609-955-4412

Sponsors and collaborators

Lead sponsor

Rutgers, The State University of New Jersey

Other

Collaborators

  • Christiana Care Health Services
  • Cooper University Health Care
  • Hackensack Meridian Health

Registry information

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Apr 24, 2026
Registry last updated
Jul 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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