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NCT Number: NCT06847906

Evaluating the Reach of Clinical Decision Support for Patients With Heart Failure

To work best, clinical decision support tools (CDS) must be timed to provide support when healthcare decisions are made, which includes virtual visits (phone or video). Unfortunately, most CDS tools are either missing from virtual visits or not designed for the unique context of virtual visits (e.g., availability of physical assessments and labs, different workflows), which could generate new inequities for patients more likely to use virtual visits. The objective of this study is to test the reach, feasibility and acceptability of a new CDS tool for heart failure with reduced ejection fraction (HFrEF) during virtual visits. This new CDS tool was developed through an iterative design process, and will be compared to an existing HFrEF CDS tool in a randomized pilot study at outpatient cardiology clinics throughout the UCHealth system.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Decision Support Systems, Clinical Cardiovascular Diseases Heart Diseases Heart Failure

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UCHealth Primary Care and Cardiology Outpatient Clinics

Aurora, Colorado, 80045, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The study subjects are potential users of the CDS, specifically clinicians with prescribing privileges who practice at one of the health system's (UCHealth) outpatient cardiology clinics. Because we are observing their prescribing behaviors in a virtual care setting (phone or video), we are also evaluating patient characteristics which could influence their prescribing decisions.

Exclusion criteria

  • Clinicians who do not practice in a UCHealth cardiology clinic.

Treatment and study plan

Iteratively designed (new) clinical decision support tool for virtual visits

Other

The new, iteratively designed clinical decision support tool includes the traditional CDS along with links to supportive tipsheets, which include one for providers on how to add an order for patients to upload vitals in their electronic health record, and one that walks patients through how to upload vitals on their own.

Traditional clinical decision support tool

Other

The traditional CDS tool is the usual care intervention, and does not include links to tipsheets to support virtual patient care.

Primary outcomes

  1. Number of CDS alerts resulting in the prescription of a recommended medication

    Time frame: 6 months

    The primary outcome is number of CDS alerts that resulted in the prescription of the medication recommended by the CDS alert. Recommended medications include either evidence-based beta blockers, sacubitril/valsartan, mineralocorticoid receptor antagonists or sodium/glucose cotransport 2 inhibitors. Prescriptions will be based on actual prescription orders instead of clinician-stated responses, given the latter may overestimate effectiveness.

Secondary outcomes

  1. Number of patients the CDS alerted for

    Time frame: 6 months

    This outcome evaluates the reach of the CDS by counting the number of patients that the CDS alerted for.

  2. Number of times a prescriber ordered at-home vitals

    Time frame: 6 months

    This outcome will count the number of times a prescriber orders patients to take their vitals at home after being exposed to the CDS tool.

  3. Number of patients who upload their vitals in the patient portal

    Time frame: 9 months

    This outcome will count the number of patients who upload their vitals into the electronic medical record.

  4. Number of alerts that were not outright dismissed

    Time frame: 6 months

    This outcome will help investigators understand if the CDS id being used or dismissed.

  5. Number of prescription orders for guideline directed medical therapy (GDMT) for heart failure

    Time frame: 6 months

    This outcome measures the number of prescriptions for each of the four categories of GDMT: evidence-based beta blockers, sacubitril/valsartan, mineralocorticoid receptor antagonists or sodium/glucose cotransport 2 inhibitors.

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Collaborators

  • American Heart Association

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Feb 26, 2025
Registry last updated
Jun 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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