Skip to main content
OpenTrials
Completed

NCT Number: NCT02003170

Etiology and Early Diagnosis of Neurodevelopmental Disorders

The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.

Completed

Looking for future studies?

Notify Me

Key information

Age range

0 month–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Arkansas Children's Hospital Research Institute

Little Rock, Arkansas, 72205, United States

About this study

Although neurodevelopmental disorders are very prevalent (for example Autism affects 1 out of every 88 children and dyslexia affects up to 15% of the population), the etiology of such disorders is not known. The purpose of this investigation is to identify common etiologies of neurodevelopmental disorders (i.e., speech delay, global developmental delay, autism) and determine if it is possible to find early indicators of the diagnosis and foster the potential for a better prognosis of these disorders. At this time the investigators examine patients with neurodevelopment disorders with various medical investigations, but the results of these investigations are not systematically evaluated. One of the goals of this research is to systematically examine this information in order to identify patterns of test abnormalities that have not been previously described. Another goal of this research is to identify the common etiologies typically identified by the medical evaluation, so we can further refine our approach. In addition, the investigators now have the ability to evaluate biological samples for biomarkers that have potential to be diagnostically useful.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Neurodevelopmental delays
  • Clinical visit at an Arkansas Children's Hospital Outpatient clinic

Exclusion criteria

  • none

Treatment and study plan

Primary outcomes

  1. Medical abnormalities associated with specific neurodevelopmental disorders

    Time frame: up to 7 years

    It is unknown if a specific set of biological abnormalities contribute to the formation of many types of neurodevelopmental disorders. The study is intended to identify the relationship between biological abnormalities and neurodevelopmental disorders

Secondary outcomes

  1. Biomarkers associated with neurodevelopmental disorders

    Time frame: up to 7 years

    It is unknown if a specific biomarkers are associated with specific neurodevelopmental disorders. The study is intended to identify the relationship between biological abnormalities and neurodevelopmental disorders

  2. Treatments associated with neurodevelopmental disorders

    Time frame: up to 7 years

    Various behavioral and medical treatments are used for many types of neurodevelopmental disorders but the effectiveness for many of these treatments is not known. The study is intended to identify the relationship between biological abnormalities (and their treatments) and neurodevelopmental disorders

Sponsors and collaborators

Lead sponsor

University of Arkansas

Other

Collaborators

  • Arkansas Children's Hospital Research Institute

Registry information

Important dates

Study start
2012
Primary completion
2024
Study completion
2024
First posted
Dec 6, 2013
Registry last updated
Jul 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.