Erector Spinae Regional Anesthesia for Pain Control

Interventional study to use erector spinae plane block (ESPB) on diagnoses of posterior or lateral rib fractures, vertebral fractures, pancreatitis, pancreatic cancer, renal colic, and back pain for multimodal pain therapy to determine its assistance with pain relief as well as the patient's use of opiates after block completion

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Key information

Conditions

Pain Management Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Early Phase 1

Primary location

Crozer Chester Medical Center, Ridley Park, Pennsylvania, United States

About this study

Patients with the listed diagnoses will be offered and then consented for an ESPB under ultrasound guidance. They will rate their pain before and 30 minutes after the procedure using the ordinal categorical data on a numeric pain scale. Total patient opiate use will be gathered up to 8 hours after block completion.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Posterior/lateral rib or vertebral fractures
Pancreatitis or pancreatic cancer
Renal colic
Back pain

Exclusion criteria

Unstable vitals
Infection or open wound over insertion site
Prior allergic reaction to local anesthetic
Pregnant females
Patients <18 years old
Altered mentation

Treatment and study plan

Bupivacaine Injection

Drug

Bucivacaine will be administered intramuscularly according to package insert directions after first numbing the area with lidocaine subcutaneously

Other names: Bupivacaine Hydrochloride Injection

Primary outcomes

Pain Scale Rating

Time frame: Baseline to study procedure end (approximately 30 minutes)

Change in pain scale rating assessed by the participants on a scale from 0-10 with 0 indicating no pain and 10 indicating the most severe pain.

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center at San Antonio

Other

Registry information

Official study title

Erector Spinae Regional Anesthesia for Pain Control in the Emergency Department

Important dates

Study start: 2023
Primary completion: 2025
Study completion: 2025
First posted: Apr 3, 2023
Registry last updated: Aug 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed