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Completed

NCT Number: NCT04221880

Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Thoracotomy

Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems. Erector Spinae Plane Block (ESPB) was first described in 2016 and, it is frequently used for postoperative analgesia in thoracic surgery. Intravenous lidocaine exhibit analgesic activity through both the peripheral and central nervous system. Intravenous lidocaine has been shown to reduce postoperative pain intensity and accelerate postoperative recovery in many surgeries.

The investigators aimed to compare the effect of lidocaine infusion and erector spinae plane block on postoperative opioid consumption and pain scores.

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Key information

Conditions

Thoracic Diseases Respiratory Tract Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ataturk University

Erzurum, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • American Society of Anesthesiologist's physiologic state I-III patients undergoing thoracotomy surgery

Exclusion criteria

  • chronic pain, bleeding disorders, renal or hepatic insufficiency, non cooperative patient,
  • Patients with allergies to one of the drugs used in the study.

Treatment and study plan

Bupivacaine Hcl 0.25% Inj

Drug

Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine

Saline Solution for Block

Drug

Ultrasound-guided erector spinae plane block with 20 ml saline

Saline Solution intravenously

Drug

Same volume saline solution bolus and infusion as Group Lidocaine

Lidocaine

Drug

1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion

Primary outcomes

  1. Opioid Consumption

    Time frame: First 24 hours total opioid consumption

    First 24 hours total fentanyl consumption with patient controlled analgesia

Secondary outcomes

  1. Visual analog pain score

    Time frame: Postoperative 24 hour

    Post operative pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain) at first hour postoperatively.

Sponsors and collaborators

Lead sponsor

Ataturk University

Other

Registry information

Official study title

Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Prospective, Randomized, Double-blind Controlled Clinical Trial

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jan 9, 2020
Registry last updated
May 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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