Endothelial Dysfunction in Reversible Cerebral Vasoconstriction Syndrome

The investigators lead a case control study to find a systemic endothelial dysfunction by the using of Complior device. Complior is a mechanographer who calculates pulse wave velocity (PWV). Pulse wave velocity is a reflect of arterial stiffness and it's correlate with endothelial dysfunction. For BHI, a Philips echograph is used before and after 30 second of breath holding.

Study protocol is :

For Patient :

• Day 0 : in hospital : anamnesis, medical history, physic examination, EKG, blood sample analysis, BHI, PWV analysis
• Month 1 : in medical visit : medical evolution, physic examination, EKG, blood sample analysis, BHI, PWV analysis
• Month 3 : in medical visit : medical evolution, physic examination, EKG, blood sample analysis, BHI, PWV analysis, cerebral angioCT Scan

For control :

• Day 0 : in hospital : medical history, physic examination, EKG, BHI, PWV analysis

Inclusion criteria

for patients :

• Aged from 18 to 80 years old
• RVCS diagnosis evoked on clinic and radiologic finding
• Last headache was 15 days ago
• Oral consent
• Register in French social security

Inclusion criteria

for control :

• Aged from 18 to 80 years old
• Hypothesis of RCVS in clinical presentation and on cerebral imaging
• Last headache less than 3 days old
• Oral consent
• Register in French social security
• Person under guardianship, curatorship or safeguarding of justice

Exclusion criteria

Non inclusion criteria for patient :

• Pregnant women
• Tobacco, coffee, alcohol, drugs or vasoactive recreational substances use within 2 hours prior to the examination.
• Person under guardianship, curatorship or safeguarding of justice
• Non sinusal rhythm on EKG
• Impossible of Breath holding for 30 secondes

Exclusion criteria

for patient :

• No reversibility at 3 months

Non inclusion criteria for control :

• Pregnant women
• Tobacco, coffee, alcohol, drugs or vasoactive recreational substances use within 2 hours prior to the examination.
• Non sinusal rhythm on EKG
• Impossible of Breath holding for 30 secondes