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NCT Number: NCT07396662

Endocrine-exocrine Functions and Prognosis After Pancreatectomy

Pancreatic diseases often require surgery or invasive procedures to provide a chance for a cure. However, due to the pancreas's unique anatomical structure, its relative position to adjacent organs, and its dual endocrine and exocrine functions, the complexity of surgery is increased, impacting the patient's postoperative quality of life. Therefore, this project aims to retrospectively collect basic data, preoperative and postoperative blood tests (blood cell counts, biochemistry, tumor markers, glucose-related, lipid-related), and preoperative and postoperative imaging examinations (CT, MRI, Ultrasound, PET scan, Endoscopy, etc.) of patients who underwent pancreatic surgery at our hospital. We aim to compare whether surgical methods, lesion margin clearance rates, and postoperative remnant pancreatic volume affect the patient's endocrine function, exocrine function, quality of life, and disease prognosis. This analysis is intended to understand the indications, surgery-related factors, and prognosis for patients planning to undergo pancreatic surgery, with the expectation of providing more diverse and specific treatment recommendations for patients with pancreatic diseases in the future

Recruiting

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Key information

Age range

20 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

National Taiwan University Hospital

Taipei, Taiwan, 10002

Location status: Recruiting

Location contact

Yu Wen Tien, Ph.D.

CONTACT

[email protected]

0972651427

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients scheduled for pancreatectomy

Exclusion criteria

  • Age under 20 years or older than 75 years; Pregnancy

Treatment and study plan

Pancreatectomy

Procedure

all procedures demanding pancreatic parenchyma transaction

Primary outcomes

  1. postoperative pancreatic endocrine-exocrine functions

    Time frame: 6 months after pancreatectomy

    • Pancreatic endocrine function will be measured by incidence of appearance of new-onset or aggravated DM after operation.
    • pancreatic exocrine function will be measured by incidence of appearance of steatorrhea which can be alleviated by replacement of digestive enzyme.

Study contacts

Contact information is provided by the study sponsor or research team.

Yu Wen Tien, Ph.D.

CONTACT

[email protected]

0972651427

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

The Analysis of Endocrine-exocrine Functions and Prognosis After Pancreatectomy

Important dates

Study start
2016
Primary completion
2034
Study completion
2034
First posted
Feb 9, 2026
Registry last updated
Feb 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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