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Recruiting

NCT Number: NCT07209072

Emergency Department Linkage to Care for Patients Experiencing Homelessness

In an effort to improve access to primary care at time of discharge, patients who are homeless will be given either enhanced follow up through a street medicine team or routine follow up in clinic.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Patients who experience homelessness frequently utilize the ED, but lack follow up primary care. In an effort to augment access to post-ED primary care, the investigators propose a quasi-experimental equivalent time sample study in which patients fitting certain diagnostic and inclusion criteria are allocated to either a) a referral to the Comprehensive Care Clinic at Denver Health, or b) a referral to Colorado Coalition for the Homeless (CCH) Stout Street medicine clinic. The street medicine clinic aims to lower barriers to access by locating patients on the street and providing primary care rather than asking patients to present to clinic. All patients will still receive the hospital appointment line number at time of discharge. 1 month and 3 months after index visit, the investigators will examine follow up rates at both clinics as well as secondary outcomes including ED visits, hospitalizations, and mortality through chart review of Denver Health and CCH electronic health records and CORHIO.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult (≥18 years of age) DHMC ED patient,
  • currently unsheltered, defined as living on the streets, in a vehicle, or in another place not fit for human habitation,
  • anticipating ED discharge, with
  • a diagnosis listed below that requires short-term follow up:
  • COPD or asthma exacerbation
  • Bacterial or viral pneumonia
  • CHF with volume overload
  • SSTI
  • Dehydration requiring IV fluids
  • Hyperglycemia secondary to DM
  • Frostbite
  • First- and second-degree burns
  • Bacterial ENT infections
  • Diabetic foot infection
  • Traumatic head injury
  • Pregnancy
  • Opioid overdose
  • a stable location (i.e., an intersection, landmark, or encampment where they can be located by the street medicine team) within Denver County for at least 2 weeks.

Exclusion criteria

  • have altered mentation (e.g., intoxication, or secondary to medical, psychiatric, or behavioral conditions) that are unable to communicate their location, contact information, or agree to follow up.
  • are prisoners,
  • previously enrolled.

Treatment and study plan

Street medicine follow up

Behavioral

This intervention will use electronic health record builds to automatically send a referral to a street medicine clinic, who will attempt to contact the patient within 2 weeks.

Primary outcomes

  1. ED visits

    Time frame: 1 and 3 months

    Repeat visits to the ED

Secondary outcomes

  1. Inpatient hospitalizations

    Time frame: 1 and 3 months

    Inpatient hospitalizations at this same hospital

  2. Mortality

    Time frame: 3 months

    Death

Study contacts

Contact information is provided by the study sponsor or research team.

Carolynn Lyle, PAC MPH

CONTACT

[email protected]

Kathleen M Joseph, MD MPH

CONTACT

[email protected]

13175194468

Sponsors and collaborators

Lead sponsor

Denver Health and Hospital Authority

Other

Registry information

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Oct 6, 2025
Registry last updated
Jan 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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