Emergency Department CT Scanning for Appendicitis

The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department. A secondary purpose will be to design a specific CT for appendicitis protocol at our institution at the conclusion of this study.

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Key information

Conditions

Appendicitis Cecal Diseases Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Infections Intestinal Diseases Intraabdominal Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis

Exclusion criteria

pregnant patients
patients with known IV dye or oral contrast allergy
patients in whom acute appendicitis is not the primary diagnosis
patients with renal insufficiency that may have significant adverse effect from IV dye

Treatment and study plan

Omnipaque

Other

oral contrast for CT scan

Primary outcomes

sensitivity of IV contrast alone for a computed tomography scan for the diagnosis of appendicitis in the adult Emergency Department patient.

Time frame: immediate reading + blinded reading within 48 hours

Secondary outcomes

If IV contrast alone for CT scan is sensitive for the diagnosis of appendicitis in the adult Emergency department patient

Time frame: immediate reading and blinded reading within 48 hours

Sponsors and collaborators

Lead sponsor

WellSpan Health

Other

Registry information

Official study title

Emergency Department CT Scanning for Appendicitis: IV Contrast vs. IV and Oral Contrast

Important dates

Study start: 2006
Primary completion: 2008
Study completion: 2010
First posted: Aug 14, 2008
Registry last updated: Jun 28, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed