Emergence Agitation in Adult Patients After Intracranial Surgery

Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy. In this prospective multicenter cohort study, adult patients will be enrolled after craniotomy and emergence agitation will be evaluated. The incidence, risk factors and outcome will be investigated.

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Key information

Conditions

Intensive Care, Surgical Confusion Delirium Emergence Delirium Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurocognitive Disorders Neurologic Manifestations Neurosurgery Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Care Postoperative Complications Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Daxing Teaching Hospital, Capital Medical University, Beijing, Beijing Municipality, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Both supratentorial and infratentorial intradural cranial operations

Exclusion criteria

Unarousable state (SAS=1) during the first 24 hours after the operation
Interval longer than 24 hours between the end of the surgery and neurosurgical ICU admission

Treatment and study plan

Anesthesia recovery after intracranial surgery

Procedure

Intracranial surgery for brain tumor, traumatic brain injury, intracranial hemorrhage, subarachnoid hemorrhage and infection.

Primary outcomes

Emergence agitation

Time frame: 12 hours after operation

Emergence agitation is measured by sedation-agitation scale (SAS) and is defined as SAS=5-7.

Sponsors and collaborators

Lead sponsor

Capital Medical University

Other

Collaborators

Beijing Municipal Administration of Hospital, China

Registry information

Official study title

Emergence Agitation During Recovery From Intracranial Surgery Under General Anesthesia: a Prospective Multicenter Cohort Study

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2015
First posted: Dec 17, 2014
Registry last updated: Aug 5, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed