Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT04670224

Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.

Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Notify Me

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

BAR

Amiens, 80054, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion criteria

  • Pregnant woman
  • Patient under 18 years of age
  • Subject under guardianship or curators
  • Patient allergic to local anesthetics
  • Infection at the puncture sites
  • Patient on morphine analgesic over the long term
  • Patient on antidepressants for neuropathic pain.

Treatment and study plan

QLB anesthesia

Other

The QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus.

Intravenous anesthesia without QLB

Other

only intravenous anesthesia

Primary outcomes

  1. Variation from baseline of morphine consumption

    Time frame: 24 hours after surgery

Secondary outcomes

  1. Variation from baseline of morphine consumption

    Time frame: 1 hour after surgery

  2. Variation from baseline of morphine consumption

    Time frame: 2 hours after surgery

  3. Variation from baseline of morphine consumption

    Time frame: 48 hours after surgery

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Acronym: QLB

Important dates

Study start
2021
Primary completion
2025
Study completion
2026
First posted
Dec 17, 2020
Registry last updated
May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.