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Completed

NCT Number: NCT02001259

Efficacy of Epidural Steroid for Controlling Pain After Primary TKA

The purpose of this study is to determine efficacy of epidural steroid for postoperative pain control after TKA

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

50 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

department of orthopaedic surgery, Faculty of medicine, Thammasat university

Khlong Luang, Changwat Pathum Thani, 066, Thailand

About this study

Epidural triamsinolone can reduce postoperative pain and longer duration of pain control after TKA

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • osteoarthritis of the knee who undergoing unilateral primary total knee arthroplasty
  • 50-85 years old
  • ASA class 1-3

Exclusion criteria

  • unable to perform epidural anaesthesia
  • history of drug allergies: lidocaine, steroid
  • renal impairment (CrCl <30 mL/min)
  • liver impairment
  • cognitive function disorders
  • displacement of epidural catheter

Treatment and study plan

epidural triamsinolone

Drug

add drugs into catheter at 48 hr after surgery

Other names: epidural steroid

epidural lidocaine

Drug

add into catheter at 48 hr after surgery

Other names: epidural xylocaine

Primary outcomes

  1. post-operative pain

    Time frame: 3 months

    measured with VAS for pain (VAS at rest and on motion)

Secondary outcomes

  1. functional knee score

    Time frame: 3 months

    measured with WOMAC

Other outcomes

  1. complication of epidural triamcinolone

    Time frame: 2 weeks

  2. range of motion of the knee

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Thammasat University

Other

Registry information

Official study title

Efficacy of Epidural Steroid in Controlling Postoperative Pain After Primary Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Dec 4, 2013
Registry last updated
May 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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