Efficacy and Prognosis of Auxiliary Liver Transplantation

The objective of this observational study is to systematically compare the efficacy and patient prognosis between auxiliary liver transplantation and living donor liver transplantation, and to explore the postoperative recovery, survival rate, rejection, postoperative complications, and long-term prognosis of patients undergoing auxiliary liver transplantation.

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Key information

Conditions

Liver Transplantation Auxiliary Liver Transplantation

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who underwent auxiliary liver transplantation or living donor liver transplantation (LDLT).
Patients with complete medical records and follow-up data.

Exclusion criteria

Patients who underwent retransplantation.
Patients who underwent other organ transplantation (or multiorgan transplantation).
Patients with severe missing postoperative follow-up data or loss to follow-up.

Treatment and study plan

Primary outcomes

Overall survival

Time frame: Within one year after liver transplantation

Secondary outcomes

Complications

Time frame: Within one year after liver transplantation

Rejection, vascular, biliary and other related complications
changes in peripheral blood lymphocytes

Time frame: within 3 months after liver transplantation

Peripheral blood lymphocytes during the early post-transplant period were compared between the auxiliary and living donor liver transplantation groups to identify differences.

Study contacts

Contact information is provided by the study sponsor or research team.

Bin Li

CONTACT

[email protected]

+8619935943688

Sponsors and collaborators

Lead sponsor

Zhi-Jun Zhu

Other

Registry information

Official study title

Efficacy and Long-term Prognosis of Auxiliary Liver Transplantation

Important dates

Study start: 2025
Primary completion: 2028
Study completion: 2029
First posted: Dec 10, 2025
Registry last updated: Dec 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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