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Completed

NCT Number: NCT03180814

Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

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Key information

Conditions

Healthy Aging

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Federal University of Pernambuco

Recife, Pernambuco, Brazil

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elderly individuals aged between 60 and 80 years
  • Young individuals aged between 18 and 30 years
  • Able to walk without assistance
  • Good understanding to perform the proposed procedures
  • Sedentary or low active

Exclusion criteria

  • Body Mass Index (BMI) > 35Kg/m2
  • Systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg (at rest)
  • Difficulty adapting to the whole body vibration
  • Smoking
  • Neuromuscular or degenerative disorders
  • Neurological diseases
  • Cardiopulmonary comorbidities
  • Cardiac arrhythmias
  • Osteoarticular disorders
  • Use of hormone replacement therapy
  • Use medications or supplements known to affect cardiovascular parameters
  • Labyrinthitis

Treatment and study plan

Whole body vibration

Other

A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.

Primary outcomes

  1. Autonomic Function

    Time frame: Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes

    Heart rate variability will be assessed from 3-channel holter

Secondary outcomes

  1. Sympathetic modulation

    Time frame: Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes

    Sympathetic modulation will be assessed from 3-channel holter

  2. Parasympathetic modulation

    Time frame: Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes

    Parasympathetic modulation will be assessed from 3-channel holter

  3. Sympathovagal Balance

    Time frame: Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes

    Sympathovagal Balance will be assessed from 3-channel holter

  4. Heart Rate

    Time frame: Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes

    Non-invasive measures will be assessed from 3-channel holter

  5. Blood pressure

    Time frame: Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes

    Non-invasive measures of brachial blood pressure

  6. Peripheral oxygen saturation

    Time frame: Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes

    Non-invasive measures will be assessed from pulse oximeter

  7. Adverse effects

    Time frame: Change from Baseline at 20 minutes

    Adverse effects reported by volunteers

Sponsors and collaborators

Lead sponsor

Universidade Federal de Pernambuco

Other

Registry information

Official study title

Acute Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Jun 8, 2017
Registry last updated
Jan 3, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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