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NCT Number: NCT04096586

Effects of Watermelon Consumption on Satiety and Digestive Health

The objective of the proposed research is to determine the effects of watermelon (fruit and rind blenderized) on satiety, metabolic markers, bowel habits, microbiome and weight management in children and adults

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Key information

Conditions

Satiety

Age range

10 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

School of Exercise and Nutritional Sciences, SDSU

San Diego, California, 92182-7251, United States

Location status: Recruiting

Location contact

Mee Young Hong

CONTACT

[email protected]

619-594-2392

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Generally healthy subjects

Exclusion criteria

  • Smoker
  • Pregnant woman
  • Required dietary supplement use
  • Required medication of metabolic disorders
  • Allergy to watermelon

Treatment and study plan

Red juice

Other

To determine the effects of red juice on satiety and gut health

Watermelon juice

Other

To determine the effects of watermelon juice on satiety and gut health

Primary outcomes

  1. Change of satiety

    Time frame: 0 and 20, 40, 60, 90 and 120 minutes post juice consumption

    Change of hunger feeling (appetite) will be examined using visual analog scale (0-10), 0 least and 10 greatest

  2. Change of glucose level

    Time frame: 0 and 20, 40, 60, 90 and 120 minutes post juice consumption

    Change of blood glucose level will be determined to examine effects of watermelon juice consumption vs red juice

  3. Change of insulin level

    Time frame: 0 and 20, 40, 60, 90 and 120 minutes post juice consumption

    Change of blood insulin level will be determined to examine effects of watermelon juice consumption vs red juice

  4. Change of triglyceride level

    Time frame: Baseline and week 8

    Change of triglyceride level with watermelon juice consumption vs red juice consumption

Secondary outcomes

  1. Change of alpha diversity in microbiome

    Time frame: Baseline and week 8

    Change of alpha diversity in micriobiome with watermelon juice consumption vs red juice consumption

Sponsors and collaborators

Lead sponsor

San Diego State University

Other

Registry information

Important dates

Study start
2019
Primary completion
2028
Study completion
2028
First posted
Sep 20, 2019
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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