Skip to main content
OpenTrials
Completed

NCT Number: NCT00157066

Effects of Vitamin D Supplementation on Antimycobacterial Immunity

The purpose of this study is to determine how vitamin D supplementation (ergocalciferol) affects the immune response to mycobacterial infection.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Tuberculosis Actinomycetales Infections Bacterial Infections Bacterial Infections and Mycoses Gram-Positive Bacterial Infections Infections Latent Infection Latent Tuberculosis Mycobacterium Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Tuberculosis Clinic, Newham Chest Clinic

London, E7 8QP, United Kingdom

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult
  • Tuberculosis (TB) contact or TB patient

Exclusion criteria

  • Pregnancy
  • Breastfeeding
  • Hyperparathyroidism
  • Sarcoidosis
  • Renal failure
  • HIV infection

Treatment and study plan

Ergocalciferol

Drug

Primary outcomes

  1. Bacillus Calmette-Guerin (BCG) lux whole blood assay

Secondary outcomes

  1. Antigen-stimulated whole blood interferon gamma production

Sponsors and collaborators

Lead sponsor

Barts & The London NHS Trust

Other

Collaborators

  • Department of Clinical Biochemistry, Homerton Hospital, London E9 6SR, UK
  • Environmental Health Department, London Borough of Newham, London E15 4SF, UK
  • Imperial College London
  • Newham Chest Clinic, London E7 8QP, UK
  • Northwick Park Hospital, Harrow, UK
  • University of Cape Town
  • Wellcome Trust

Registry information

Official study title

Effects of Vitamin D Supplementation on Antimycobacterial Immunity: A Randomised Trial

Important dates

Study start
2002
Study completion
2006
First posted
Sep 12, 2005
Registry last updated
Jan 8, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.