Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor

The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.

This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.

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Key information

Conditions

Bone Mass Effects of Vibration Sclerosteosis

Age range

20 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Bagcilar Training & Research Hospital

Istanbul, Turkey (Türkiye)

About this study

A total of 20 voluntaries are planned to include in this study.

Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.

The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.

Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 20-40 yrs
Gender: Male
Volunteer
Healthy status: Patients having hypoesthesia in his leg and Healthy subjects
Dominant hand:Right-handed

Exclusion criteria

Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),
Systemic diseases (cardiovascular, endocrine, infections etc),
Myopathy-tendinopathy
Lower limb joint disease
Vertigo
Obesity (BMI >30 kg/m2)
Professional sportsman
Male doing regular sports activities
Skin disease in lower limb
Non-cooperative subject
Hemolysis of blood sample

Treatment and study plan

Whole-Body Vibration

Other

Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec

Other names: Cyclic mechanical loading

Primary outcomes

Vibration-induced contralateral muscle electrical activity

Time frame: 3 month

Sponsors and collaborators

Lead sponsor

Bagcilar Training and Research Hospital

Other Gov

Registry information

Official study title

The Effects Of Femur On The Resting Myoelectrical Activity Of Contralateral Adductor Muscle During Unilateral Lower Extremity Vibration: Bone Myoregulation Reflex

Acronym: WBV-BM

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Aug 18, 2011
Registry last updated: May 7, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed