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Completed

NCT Number: NCT07534605

Effects of Ultrasound Therapy in Iliotibial Band Syndrome

The aim of this study is to investigate the effect of ultrasound (US) therapy, administered in different modes, on pain, functionality, quality of life and iliotibial band (ITB) thickness in patients with iliotibial band syndrome (ITBS). The primary question of the study is: Is US therapy effective in reducing pain and improving functionality in ITBS? The secondary question is: Is US therapy effective in ITBS in terms of quality of life and ITB thickness? 75 participants were assigned to the exercise, exercise plus continuous US and exercise plus intermittent US groups and received 15 treatment sessions. Participants were assessed before treatment, at the end of treatment (after 15 sessions) and at 3 months post-treatment.

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Key information

Age range

45 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Prof.Dr.Cemil Taşcıoğlu Şehir Hastanesi

Istanbul, Şişli, 34384, Turkey (Türkiye)

About this study

The aim of this study is to investigate the effects of ultrasound (US) therapy, administered in different modes, on pain, functionality and iliotibial band (ITB) thickness in patients with iliotibial band syndrome (ITBS). Seventy-five volunteers presenting at the Physical Medicine and Rehabilitation Clinic with lateral knee pain and thigh pain were included in the study. Patients aged between 45 and 60 years who met the inclusion and exclusion criteria and had been diagnosed with ITBS were enrolled in the study. The patients were divided into three groups and received 15 treatment sessions. Group 1 received exercise only, Group 2 received exercise plus continuous ultrasound, and Group 3 received exercise plus intermittent ultrasound treatment. Patients' pain scores were assessed using the Visual Analogue Scale (VAS), lower limb functionality using the Lower Limb Functionality Scale (LEFS), and quality of life using the Short Form-12 (SF-12) questionnaire before treatment, after treatment, and at the 3-month post-treatment mark. In patients diagnosed with ITBS,ITB thickness was measured ultrasonographically at the attachment point of the lateral femoral epicondyle in the lateral lying position with the knee flexed at 20-30 degrees.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

- Aged between 45 and 60 years -Patients diagnosed with ITBS using ITB trigger point palpation and the Noble compression test -Visual Analogue Scale (VAS) score ≥50 mm

Exclusion criteria

  • History of lower limb surgery within the last six month- Body weight exceeding 120 kg- History of malignancy-Severe coxarthrosis-Severe osteoporosis-Stage 4 gonarthrosis-Lower limb surgey in the last 6 months-History of any neurological, vascular or infectious disease

Treatment and study plan

Exercise

Behavioral

Hip and knee strengthening, core muscle strengthening, and ITB stretching exercises were given in 15 sessions.

Continious Ultrasound

Device

2 W/cm² intensity, 1.5 MHz frequency, 7 minutes, 15 continuous ultrasound sessions.

Intermittant ultrasound

Device

2 W/cm² intensity, 1.5 MHz frequency, 7 minutes per session, 15 pulsed ultrasound treatments.

Primary outcomes

  1. VAS and LEFS

    Time frame: Before treatment, at the end of treatment (after 15 sessions) , and 3 months after treatment.

    Pain intensity was assessed using the VAS. Patients were asked to mark their pain levels on a straight line ranging from 0 to 10 cm; 0 denoted no pain, whilst 10 denoted severe pain.Lower limb functional status was assessed using the LEFS scale. The scale, consisting of a total of 20 items, was scored according to five numerical response categories ranging from 0 (extreme difficulty/unable to perform the activity) to 4 (no difficulty). The total score was assessed on a scale of 0 to 80. Higher scores were associated with better functional status

Secondary outcomes

  1. SF-12 and ITB thickness

    Time frame: Before treatment, at the end of treatment (after 15 sessions) , and 3 months after treatment.

    General physical and mental health status was assessed using the Short Form-12 (SF-12), a 12-item version of the SF-36. Higher scores were associated with a better quality of life. The thickness of the ITB was assessed using an USG scanner.

Sponsors and collaborators

Lead sponsor

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Other

Registry information

Official study title

Effects of Ultrasound Therapy in Patients With Iliotibial Band Syndrome

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 16, 2026
Registry last updated
Apr 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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