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Completed

NCT Number: NCT07116993

Effects of Ultrasound and Infrared on Joint Pain and Movement in Hemophilia A Patients.

The study aims to compare the effectiveness of therapeutic ultrasound and infrared in managing hemarthrosis in patients with Hemophilia A, focusing on specific outcomes like joint pain, swelling, muscle atrophy, and range of motion.The main question to it is either one from both of the modalities are effective for hemophilia patients or not? comparison will be done to check the effectiveness of ultrasound and infrared on patients of both groups.

participants will:

1. get the treatment according to their respective groups 2. Both groups were given 4 sessions for 4 weeks.

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Key information

Conditions

Hemophilia A Blood Coagulation Disorders Blood Coagulation Disorders, Inherited Coagulation Protein Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhagic Disorders

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Danyal Ahmad

Sialkot, Punjab Province, 51010, Pakistan

About this study

The data collection was started by the consent of the participants through the consent form. Then we randomly divided the patients into Group A and Group B. Group A participants were given Ultrasound therapy for 10 minutes with intensity of 1.5 W/m2 along with the conventional physiotherapy as well as home plan. Group B participants were given Infrared therapy for 10 minutes with moderate intensity along with the conventional physiotherapy as well as home plan. Both groups were given 4 sessions for 4 weeks.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with hemophilia A (Eid & Aly, 2015) .
  • Who had the Bleeding frequency of atleast once per week (Eid & Aly, 2015).
  • Males with hemophilia A
  • Irrespective of their therapeutic regime administered by their hematologists (Donoso-Úbeda, Meroño-Gallut, López-Pina, & Cuesta Barriuso, 2020) .

Exclusion criteria

  • Patients who had surgical procedures (Eid & Aly, 2015) .
  • Patients who were suffering from co-morbidities along with Hemophilia A.
  • Patients who had any other disability/deformity.
  • Who were receiving other physiotherapy treatment (Donoso-Úbeda et al., 2020) .
  • Who failed to sign the informed consent (Donoso-Úbeda et al., 2020)

Treatment and study plan

theraputic ultrasound

Device

Ultrasound is a mechanical sound wave with frequencies above human hearing, requiring a medium like air or tissue to travel, commonly used in imaging.

infrared radiation

Device

Infrared, in contrast, is electromagnetic radiation associated with heat, doesn't need a medium, and is used in applications like thermal imaging and remote controls.

Primary outcomes

  1. joint pain

    Time frame: 3 weeks

    Joint Pain: Measured using the Numerical Pain Rating Scale (NPRS) to quantify changes in pain severity. 0 indicates no pain while 10 indicates severe pain

  2. ROM

    Time frame: 3 weeks

    Range of Motion (ROM): Measured using a goniometer to assess improvements in flexion and extension angles, measured in degrees, in the joint.

  3. Swelling

    Time frame: 3 weeks

    Assessed based on circumference measurements around knee, elbow and ankle joint using inelastic tape measure in centimeters around the affected joint to detect reductions in swelling.

Sponsors and collaborators

Lead sponsor

Danyal Ahmad

Other

Registry information

Official study title

Comparative Effects of Ultrasound and Infrared on Pain, Range of Motion and Joint Health in Knee, Elbow and Ankle Joints in Patients With Hemophilia A: a Randomized Clinical Trial

Acronym: Hemophilia A

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Aug 12, 2025
Registry last updated
Aug 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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