Skip to main content
OpenTrials
Completed

NCT Number: NCT04439630

Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans

Postprandial effects of Nopal fractions on glucose and appetite regulation will be investigated in healthy humans, in a randomised controlled crossover trial

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Glucose Tolerance Appetite Sensations

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Food Technology, engineering and Nutrition, LTH, Lund University

Lund, 22100, Sweden

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy
  • non-smokers
  • diet accordance with the Nordic Nutrition Recommendations
  • BMI: 18.5-25 kg/m2

Exclusion criteria

  • metabolic disorders
  • food allergies
  • no probiotics or other food /supplement which may interfere with the study

Treatment and study plan

Nopal fractions

Dietary Supplement

Nopal flour were divided in two fractions and mixed in two different test breads

Test product without the active components

Dietary Supplement

Test product without the active components

Primary outcomes

  1. postprandial glucose tolerance

    Time frame: 0-180 min after start of the meal

    effects on postprandial glucose tolerance after intake of test products at breakfast. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

  2. postprandial insulin concentrations

    Time frame: 0-180 min

    effects on serum insulin concentrations after intake of test products at breakfast. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

Secondary outcomes

  1. subjective appetite variables

    Time frame: 0-180 min

    Subjective appetite variables (hunger, satiety, desire to eat) after intake of test products at breakfast, using a 100 mm Visual Analogue Scale (VAS) on a white paper. Except from a center mark in the center of the scale there was no other visible marks. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

Sponsors and collaborators

Lead sponsor

Lund University

Other

Registry information

Official study title

Evaluation of Potentially Bioactive Foods With Regard to Their Effects on Cardiometabolic Test Markers and Cognitive Variables

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jun 19, 2020
Registry last updated
Oct 5, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.