Homburg Cream & Sugar Study

The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and to determine, whether measurement of triglyceride tolerance can discriminate patients at risk for cardiovascular events.

Completed

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Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Disease Diabetes Diabetes Mellitus Dyslipidemias Endocrine System Diseases Glucose Metabolism Disorders Glucose Tolerance Heart Diseases Hyperinsulinism Hyperlipidemia Hyperlipidemias Insulin Resistance Lipid Metabolism Disorders Metabolic Diseases Metabolic Syndrome Myocardial Ischemia Nutritional and Metabolic Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Homburg / Saar - Cardiology Department

Homburg, Saarland, 66421, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Stable CAD

Exclusion criteria

Acute Coronary Syndrom
Relevant Arrhythmias
Severe valvular heart disease
Decompensated heart failure
Severe inflammtory disease (infectious, rheumatoid)
Metabolic diseases (e.g. thyroid)
Inability to swallow
Liver or kidney failure
Lactose intolerance
Fat intolerance (e.g. chronic pancreatitis, gall stones)
Malignant Disease
Psychiatric Diseases (including alcohol / drug abuse)
Pregnancy

Treatment and study plan

Primary outcomes

Parameters of triglyceride tolerance and glucose tolerance in correlation to cardiovascular events, cardiovascular mortality, total mortality.

Time frame: 48 months after inclusion.

Secondary outcomes

Waist-to-Hip ratio, nutrition protocol, physical activity, non-invasive endothelial function, body fat composition, other biomarkers of lipid and glucose metabolism.

Time frame: Directly after inclusion.

Sponsors and collaborators

Lead sponsor

Universität des Saarlandes

Other

Registry information

Official study title

Prospective Investigation of the Influence of Triglyceride Tolerance on Cardiovascular Outcomes in Patients With Coronary Artery Disease

Acronym: HCS

Important dates

Study start: 2008
Primary completion: 2013
Study completion: 2013
First posted: Mar 5, 2008
Registry last updated: Dec 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed