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OpenTrials
Completed

NCT Number: NCT03651869

Effects of Nicotine in Tobacco Smokers

This study will examine mechanisms linking Obsessive-Compulsive Disorder symptomatology to tobacco dependence.

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Key information

Conditions

Smoking, Tobacco Behavior Behavior, Addictive Compulsive Behavior Impulsive Behavior Smoking Smoking (Tobacco) Addiction Tobacco Smoking Tobacco Use

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

University of Southern California

Los Angeles, California, 90033, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least 21 years old
  • Daily smoking at least 2 years

Exclusion criteria

  • Currently pregnant or breastfeeding.

Treatment and study plan

Cigarette 1

Drug

Cigarette containing between 0mg nicotine and the conventional amount of nicotine (0.8mg)

Cigarette 2

Drug

Cigarette containing between 0mg nicotine and the conventional amount of nicotine (0.8mg)

Patch 1

Drug

A patch containing between 0mg nicotine and the conventional amount of nicotine (21mg)

Patch 2

Drug

A patch containing between 0mg nicotine and the conventional amount of nicotine (21mg)

Primary outcomes

  1. Smoking Urge

    Time frame: Throughout study completion, an average of two weeks.

    Smoking urge is measured using questionnaires that ask about a desire to smoke.

Sponsors and collaborators

Lead sponsor

University of Southern California

Other

Collaborators

  • Illinois Institute of Technology

Registry information

Official study title

Mechanisms Linking Obsessive-Compulsive Symptoms and Tobacco Dependence

Important dates

Study start
2019
Primary completion
2023
Study completion
2023
First posted
Aug 29, 2018
Registry last updated
Jul 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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