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NCT Number: NCT01896024

Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder

The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in the early-phase treatment of patients diagnosed with Borderline Personality Disorder.

The investigators intend to include N = 80 outpatients diagnosed with Borderline Personality Disorder, consulting at the Outpatient Personality Disorder Program of the Karl Jaspers Clinical Unit, in collaboration with the Institute of Psychotherapy, at the Department of Psychiatry-CHUV, University of Lausanne and in collaboration with the University of Berne, Switzerland. Patients are assigned by chance to two treatment conditions 1) Control condition (General Psychiatric Management; Gunderson & Links, 2008) and 2) MOTR-condition. The investigators hypothesize better results in the MOTR-condition, as compared to the control condition in terms of symptom reduction pre-post.

The conduct of the study represents a significant contribution to the understanding and enhancement of relationship aspects in the treatment of patients diagnosed with Borderline Personality Disorder which may be of potential benefit for these patients.

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Key information

Conditions

Borderline Personality Disorder Mental Disorders Personality Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Psychiatry-CHUV, University of Lausanne

Lausanne, Canton of Vaud, 1004, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DSM-IV Borderline Personality Disorder;
  • between 18 and 65 yrs of age

Exclusion criteria

  • DSM-IV psychotic disorders,
  • mental retardation,
  • substance abuse in the forefront

Treatment and study plan

Psychiatric Management

Behavioral

Motive-oriented therapeutic relationship/Plan Analysis

Behavioral

Primary outcomes

  1. Outcome Questionnaire -45.2 (Lambert et al., 2004)

    Time frame: 3 months

    pre- post- intervention in a randomized controlle trial; measure of symptom reduction over 3 months

Secondary outcomes

  1. Inventory of Interpersonal Problems (Horowitz et al., 1988)

    Time frame: 3 months

    Measure of interpersonal problems after 3 months of therapy

Other outcomes

  1. Borderline Symptom List (Bohus, 2009)

    Time frame: 3 months

    Symptom reduction of borderline symptoms over 3 months of treatment

Sponsors and collaborators

Lead sponsor

University of Lausanne Hospitals

Other

Registry information

Acronym: MOTR

Important dates

Study start
2010
Primary completion
2013
Study completion
2014
First posted
Jul 11, 2013
Registry last updated
Dec 2, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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