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OpenTrials
Completed

NCT Number: NCT06927700

Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes

This study will be an online survey experiment conducted with adults who smoke cigarettes (ages 21+) to examine their reactions to modified risk advertising claims authorized by the Food & Drug Administration (FDA) for two smokeless tobacco brands (General Snus and Copenhagen), which describe the lower risks of these products compared to cigarette smoking. The study will compare effects of ads with different two different claim types (i.e. claims about reduced lung cancer risk and claims about reduced risks for multiple disease) versus ads with no reduced-risk claims, and examine effects on message and product perceptions, and interest in using the smokeless tobacco products. This study will also examine how smokers' reactions/interest may vary based on the product brand, and asses prior awareness/exposure to the authorized claims.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Rutgers Institute for Nicotine & Tobacco Studies

New Brunswick, New Jersey, 08901, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (age 21 and over) who are current established cigarettes smokers (i.e., smoked 100 cigarettes in their lifetime and now smoke every day or somedays), based in the US, members of Ipsos' KnowledgePanel, and have chosen to complete their research panel surveys in English

Exclusion criteria

  • Panel participants who do not meet the criteria outlined above will be excluded.

Treatment and study plan

Modified Risk Claim Type - None

Behavioral

Participants will view smokeless tobacco ads with no modified risk claim (control)

Product Brand - General Snus

Behavioral

Participants will views ads for the smokeless tobacco brand General Snus

Product Brand - Copenhagen

Behavioral

Participants will views ads for the smokeless tobacco brand Copenhagen

Modified Risk Claim Type - Multiple Diseases

Behavioral

Participants will view smokeless tobacco ads with a claim about lower risks for multiple diseases

Modified Risk Claim Type - Lung Cancer

Behavioral

Participants will either view smokeless tobacco ads with a modified risk claim about lower risks for lung cancer only

Primary outcomes

  1. General Relative Harm Perception

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    Single item measure asking participants how harmful they think daily use of the viewed smokeless tobacco product would be to their health compared to daily cigarette smoking, (1=a lot less harmful, 2=somewhat less harmful, 3=about the same, 4=somewhat more harmful, 5=a lot more harmful). Higher scores mean thinking the viewed smokeless tobacco product is more harmful than cigarettes.

  2. Perceptions of Perceived Relative Risks of Diseases

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    Assessment of perceived risks of getting various smoking related diseases from using the viewed smokeless tobacco product versus from smoking cigarettes. Responses to 6 parallel questions (each asking about a different disease) were averaged together in this composite item. The question stated: "If you used only [General Snus/Copenhagen - inserted based on brand condition] or only cigarettes every day, which product would make it more likely that you would get": 1) lung cancer; 2) heart disease; 3) mouth cancer; 4) stroke; 5) chronic bronchitis; 6) emphysema. Response options to each were on a 5 point scale from (1=much more likely with General Snus/Copenhagen to 5=much more likely with cigarettes). Results presented here are based on the averages responses to the six items. Higher scores mean thinking risks are greater from smoking cigarettes than from using the viewed smokeless tobacco product.

  3. Absolute Harm Perception

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    Single item measure asking participants how likely or unlikely they think the viewed smokeless tobacco product would be to cause serious health problems during their lifetime, if they used it every day (from 1=not at all likely to 5=extremely likely). Higher scores mean greater likelihood of thinking the product is harmful to health.

  4. Product Use Intentions

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    Assessment of intentions to use the viewed smokeless tobacco products based on averaging responses to three parallel questions: "Thinking about the ads you saw for [General Snus or Copenhagen] products, how interested, in the next 6 months, would you be in: 1) Using or trying these products? 2) Using these products as a way to quit or cut down on your cigarette smoking? 3) Completely switching from cigarettes to these products? Response options to each were on a 5 point scale from (1=not at all interested to 5=extremely interested). Results presented here are based on the averaged responses to these three items. Higher scores mean greater interest in using the products.

Secondary outcomes

  1. Risk Message Recall

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    Participants are asked to recall (yes/no) if the ads they viewed include any statement saying that using the product can lower risks of certain diseases.

  2. Ad Persuasiveness

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    A composite measure based on the average of 6 advertisement perceptions, asking participants to rate whether they agreed or disagreed that they ads they viewed: 1) included important information; 2) were understandable; 3) included believable information; 4) included credible information; 5) included information new to me; 6) make me want to learn more about those products. Response options were on a 6 point agreement scale from 1=strongly disagree to 6=strongly agree. Higher scores mean greater agreement that the ads were effective and persuasive.

  3. Claim Believability & Credibility

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    A composite measure based on the average of 2 claim perception items, asking participants to rate whether they agreed or disagreed that the modified-risk claim in the ads they viewed was : 1) believable 2) credible. Participants responded to this while seeing the claim again on the survey screen. Response options were on a 7 point agreement scale from 1=strongly disagree to 7=strongly agree. Higher scores mean greater agreement that the claims were believable and credible.

  4. Overall Perceived Claim Persuasiveness

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    A composite measure based on the average of 7 claim perception items, asking participants to rate whether they agreed or disagreed that the modified-risk claim in the ads they viewed was : 1) believable; 2) credible; 3) important; 4) new to me; 5) makes me think using this product could be less harmful to my health than smoking; 6) makes me more interested in trying this product; 7) would make me think seriously about completely switching to this product. Participants responded to this while seeing the claim again on the survey screen. Response options were on a 7 point agreement scale from 1=strongly disagree to 7=strongly agree. Higher scores mean greater agreement that participants thought the claim was persuasive/effective.

  5. Switching Comprehension

    Time frame: Assessed in survey measures completed immediately after viewing the study stimuli

    An item assessing participants' understanding of the need to completely switch to the smokeless tobacco product viewed in order to reduce risks. It said:

    Please answer the next question based on your understanding of the ads you viewed earlier. Based on the ads, [General Snus OR Copenhagen, inserted based on condition] can reduce a smoker's health risks if you: (Select all that apply)

    • Use only [General Snus/Copenhagen] and not smoke any cigarettes anymore
    • Use [General Snus/Copenhagen] and smoke fewer cigarettes than before
    • Use both products ([General Snus/Copenhagen] and cigarettes) about equally
    • None of the above
    • I don't know/not sure

Sponsors and collaborators

Lead sponsor

Rutgers, The State University of New Jersey

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 15, 2025
Registry last updated
Mar 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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