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OpenTrials
Completed

NCT Number: NCT00520858

Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

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Key information

Age range

65 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Queen's University

Kingston, Ontario, K7L 3N6, Canada

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men and women between 65 and 80 years of age.
  • Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
  • We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion criteria

  • Smokers and diabetics.
  • Women taking hormone replacement therapy.

Treatment and study plan

Resistance Exercise (RE)

Other

Aerobic Exercise (AE)

Other

Resistance and Aerobic Exercise (RAE)

Other

Primary outcomes

  1. Abdominal obesity

    Time frame: 6 months

Secondary outcomes

  1. Insulin Resistance

    Time frame: 6 Months

Sponsors and collaborators

Lead sponsor

Queen's University

Other

Collaborators

  • Canadian Institutes of Health Research (CIHR)

Registry information

Important dates

Study start
2003
First posted
Aug 27, 2007
Registry last updated
Apr 22, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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