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OpenTrials
Completed

NCT Number: NCT07422415

Effects of E-Cigarette Use Among Young Egyptian Adults

Electronic cigarettes (E-cigarettes) have gained significant popularity as an alternative to traditional combustible tobacco cigarette smoking. E-cigarettes are marketed as a safer alternative to conventional smoking forms. Many chronic smokers suppose that e-cigarettes are risk-free and can be used effectively as a smoking cessation tool. The market size of e-cigarette is increasing because of its rising popularity among the youth even though it is not an approved Food and Drug Administration (FDA) product yet

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

About this study

Most daily life activities as walking and household chores that affect quality of life are performed at a submaximal level of exertion. E-cigarettes may affect overall physical fitness and cardiovascular health. It is important to evaluate responses of all body systems interacting during exercise, including cardiovascular and pulmonary function, systemic circulation, peripheral circulation, blood, neuromuscular units, muscle metabolism, oxygen transport and utilization within skeletal muscles. The knowledge gap regarding the potential negative health effects of E-cigarettes is crucial, as e-cigarettes are newly prevailing smoking tools that are gaining rising popularity among the youth. Additionally, the false perception of the unregulated electronic cigarette smoking as a safe recreational habit may increase the prevalence among the population. The aim of this work is to assess the clinical and functional impact of E-cigarettes garette use in young Egyptian adults, and to evaluate the role of chest CT in follow-up of identified abnormalities.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age > 18 years
  • E-cigarette users (≥6 months of regular use)
  • No prior history of chronic pulmonary disease

Exclusion criteria

  • Dual users (both e-cigarettes and traditional tobacco)
  • History of chronic respiratory illnesses (e.g., asthma, COPD)
  • immunocompromised
  • Systemic chronic diseases

Treatment and study plan

Pulmonary Function Test

Diagnostic Test

Spirometry was performed measure forced expiratiory volume at 1st second (FEV₁), forced vital capacity (FVC), and FEV₁/FVC ratio.

Primary outcomes

  1. Spirometer parameters assessment

    Time frame: 3 months

    Spirometry was performed to measure forced expiratory volume at 1st second (FEV₁)

  2. Spirometer assessment

    Time frame: 3 months

    Spirometry was performed to measure FEV₁/FVC ratio

  3. Spirometer

    Time frame: 3 months

    Spirometry was performed to measure forced vital capacity (FVC)

Sponsors and collaborators

Lead sponsor

Mansoura University Hospital

Other

Registry information

Official study title

Respiratory, Functional, and Radiological Effects of E-Cigarette Use Among Young 1 Egyptian Adults: A Cross-Sectional Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Feb 20, 2026
Registry last updated
Feb 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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