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Completed

NCT Number: NCT02996786

Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational Runners

The aim of this study is to examine the beneficial effects of Danggui Buxue Tang on blood biochemical parameters in male recreational runners.

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Key information

Conditions

Sports Anemia Fatigue Hemolysis Inflammation Iron Deficiencies Iron Deficiency Iron Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Oxidative Stress Pathologic Processes Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Kaohsiung Medical University

Kaohsiung City, 807, Taiwan

About this study

  • Male recreational runners would be recruited by community websites or email. After completely introducing the study, the participants would be requested to sign informed consent.
  • The participants would perform maximal oxygen consumption test prior to the supplementation. The participants would be supplemented with either Danggui Buxue Tang or placebo for a week before performing the 13-km run. A total of 4 times blood collection (before supplementation, immediate after running, 1 day and 3 days after running) would be performed for evaluating the effect of Danggui Buxue Tang on blood biochemical parameters.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The participants should have the experience finishing 10-km run but without the experience of attending a marathon run.

Exclusion criteria

  • Participants suffering from anemia (Hb <13 g/dL), taking usual supplements, medication, alcohol or not feeling comfortable.

Treatment and study plan

Danggui Buxue Tang

Dietary Supplement

Danggui Buxue Tang purchased from Kaiser Pharmaceutical

Placebo

Other

Consisting of corn starch and carboxymethyl cellulose

Primary outcomes

  1. Hematological parameters

    Time frame: Through study completion, an average of 1 year

    Complete blood counts and serum haptoglobin and erythropoietin

  2. Iron status

    Time frame: Through study completion, an average of 1 year

    Serum iron, ferritin, transferrin and hepcidin

  3. Oxidative stress

    Time frame: Through study completion, an average of 1 year

    Thiobarbituric acid reactive substances, superoxide dismutase, catalase, and glutathione peroxidase

  4. Inflammatory response

    Time frame: Through study completion, an average of 1 year

    High-sensitivity c-reactive protein, Tumor necrosis factor-alpha, and interleukin-6

Secondary outcomes

  1. Running time

    Time frame: Through study completion, an average of 1 year

    The completion time for a 13-km run

Sponsors and collaborators

Lead sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Dec 19, 2016
Registry last updated
Apr 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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