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Completed

NCT Number: NCT06483633

Effects of Combining Different Exercise Modes With CPT on Vascular Function and Sleep Quality in Female University Students With SD

Fourteen female college students with sleep disorders (SD) and fourteen with good sleep status were recruited, divided into sleep disorder group (SDG) and control group (CG). Both groups underwent moderate-intensity continuous training (MICT), high-intensity interval training (HIIT), and sprint interval training (SIT). Immediately after exercise, Cold Pressor Test (CPT) was administered, vascular indicators were measured immediately and 30 minutes later. The next day after exercise, participants completed the Pittsburgh sleep quality index (PSQI). Each exercise mode had a washout period of at least 7 days.

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Key information

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

School of Sports Medicine and Rehabilitation, Beijing Sport University

Beijing, China

About this study

Both SDG and CG underwent HIIT, MICT, and SIT interventions. After the exercise, a CPT was conducted, and vascular indicators were immediately measured at the end of the intervention. Another measurement was taken 30 minutes after the intervention. The exercise was performed on a power bike, with the requirement to maintain a pedaling frequency of 60 rpm. The exercise protocols for HIIT, MICT, and SIT were designed with equal exercise volume. The HIIT protocol consisted of 4 sets of 4 minutes at 85% maximal oxygen uptake data (VO2max), interspersed with 3 minutes at 50% VO2max. The MICT protocol involved continuous pedaling at 60% VO2max for 32 minutes. The SIT protocol included 6 sets of 30-second all-out sprints (100% VO2max) with 4.5 minutes of recovery at 60% VO2max between each sprint. There was a minimum of 7 days between each exercise mode as a washout period. The PSQI questionnaire was completed the day after each intervention upon waking up.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female university students aged between 18 and 30 years old
  • Body Mass Index (BMI) between 18.5~24.0 kg/m2
  • Presence of SD (PSQI > 8 points) or good sleep quality (PSQI ≤ 7 points)
  • Not taking medications that affect sleep
  • No cardiovascular diseases
  • No regular exercise habits or specialized training but possessing the ability to complete the exercise program

Exclusion criteria

  • Severe organic diseases such as heart, kidney, etc
  • Metabolic diseases such as diabetes, etc.
  • Taking medications that affect sleep (including drugs that promote or interfere with sleep)
  • Permanent and severe exercise dysfunction
  • Participation in other experiments

Treatment and study plan

MICT + CPT, HIIT + CPT, SIT + CPT

Behavioral

Single acute intervention, each exercise mode had a washout period of at least 7 days.

Primary outcomes

  1. Pittsburgh Sleep Quality Index

    Time frame: The next morning following each intervention, within 24 hours post-intervention

    The change of Pittsburgh Sleep Quality Index (PSQI) before and after the intervention, Pittsburgh Sleep Quality Index include: specifically PSQI total score, sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, and daytime functioning.

  2. Ankle-brachial pulse wave velocity (baPWV)

    Time frame: Immediately after each intervention and 30 minutes later.

    The change of baPWV before and after intervention.

  3. Ankle-brachial index (ABI)

    Time frame: Immediately after each intervention and 30 minutes later.

    The change of ABI before and after intervention.

Secondary outcomes

  1. Blood pressure

    Time frame: Immediately after each intervention and 30 minutes later.

    The change of blood pressure before and after intervention.

Sponsors and collaborators

Lead sponsor

Beijing Sport University

Other

Registry information

Official study title

Effects of Combining Different Exercise Modes With Cold Pressor Test on Vascular Function and Sleep Quality in Female University Students With Sleep Disorders

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Jul 3, 2024
Registry last updated
Jul 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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