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Completed

NCT Number: NCT00477854

Effects of Chromium Picolinate on Food Intake

The purpose of this study is to test the effects of chromium picolinate on food intake, food cravings, eating attitudes, and appetite. If chromium picolinate is found to have a beneficial impact on satiety and food intake, then this supplement may be an alternative or adjunctive treatment for overweight people desiring to modify their food intake. The primary hypothesis of this study is that among individuals who report being carbohydrate cravers, chromium picolinate supplementation will reduce food intake during a test lunch meal and produce greater satiety in comparison to a placebo.

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Key information

Age range

18 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Inclusion criteria

are:

  • Healthy female who has not been diagnosed with diabetes, cardiovascular illness, or other chronic diseases,
  • Food craver, determined by self-reported craving for carbohydrates on two out of three validated measures of food cravings,
  • > 18 years of age and < 50 years of age, and
  • Body mass index between 25 and 39.9 kg/m2. Participants will be scheduled for testing during the luteal phase of their menstrual cycle to limit the confounding effect of the menstrual cycle on energy intake. We will include women who are taking monophasic oral contraceptives but will exclude other oral contraceptive regimens. Participants with very irregular menstrual cycles will also be excluded because this irregularity will make it very difficult to schedule testing during the luteal phase of the menstrual cycle.

Exclusion criteria

Potential participants will be excluded for the following reasons:

  • Participants who report smoking cigarettes will be excluded because of the effects of nicotine upon taste and appetite,
  • Participants who have a diagnosable eating disorder (i.e., anorexia or bulimia nervosa) will also be excluded since intentional restriction of eating and binge eating/overeating could increase the variability of the data,
  • Participants who report using diet pills will be excluded since diet pills may potentially influence appetite, hunger, and/or satiety,
  • Participants will be excluded if they are taking anti-depressant medications, anti-psychotic medications, or any medications that may potentially influence appetite, hunger, and/or satiety,
  • Participants who are not determined to be carbohydrate cravers will be excluded,
  • Participants will also be excluded if they report any allergies to the foods that will be used in the study.

Treatment and study plan

Chromium Picolinate

Drug

Test whether Chromium Picolinate supplementation affects food intake at both a test lunch meal and at a test dinner meal presented 4.5 hours later among healthy, overweight and/or obese, adult women who are determined to be carbohydrate creavers.

Primary outcomes

  1. Food intake at both a test lunch meal and at a test dinner meal presented 4.5 hours later

    Time frame: 8 weeks

Secondary outcomes

  1. Hunger and satiety between the lunch and dinner meal

    Time frame: 8 weeks

Sponsors and collaborators

Lead sponsor

Pennington Biomedical Research Center

Other

Collaborators

  • Nutrition 21, Inc.

Registry information

Official study title

Effects of Chromium Picolinate on Food Intake, Satiety, and Eating Attitudes in Overweight Women With Food Cravings

Important dates

Study start
2005
Primary completion
2007
Study completion
2007
First posted
May 24, 2007
Registry last updated
Feb 12, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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