Skip to main content
OpenTrials
Completed

NCT Number: NCT05563493

Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible.

Impaired pulmonary functions, decreased exercise capacity and quality of life and increased dyspnea perception is prevalent in patients with acute exacerbations of COPD.It was demonstrated exercise training has beneficial effects in patients with acute exacerbations of COPD.

The purpose of this study to evaluate the effects of chair-based exercise training on exercise capacity, respiratory functions, dyspnea, balance, depression anxiety and quality of life in COPD patients in acute exacerbation.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Necmettin Erbakan University Nezahat Keleşoğlu Faculty of Health Sciences

Konya, 42090, Turkey (Türkiye)

About this study

Acute exacerbations of COPD are generally defined as events in the natural course of the disease characterized by a change in the patient's initial dyspnea, cough or sputum beyond normal daily variations. The main consequences of COPD in acute exacerbation are increased mortality, deterioration in health-related quality of life, faster decline in lung function, marked reduction in physical activity and worsening of peripheral muscle weakness, which have a direct impact on patients' health. Although exacerbations are diagnosed based on respiratory symptoms, there is evidence that they have systemic consequences, including a detrimental effect on skeletal muscle function, exercise tolerance and quality of life.

Chair-based exercise training is defined as a structured and progressive exercise program applied by trainers that provides stability using a chair, which is a part of exercise training for the elderly. It is thought that it would be beneficial to study such an exercise program, since COPD patients in acute exacerbation have less mobilization during hospitalization.

In a limited number of studies, some inconsistencies were observed in the exercises of patients with acute exacerbation of COPD. Studies can therefore now focus on investigating comparisons between different intervention lengths, session durations and frequencies, and intensities of exercise training. For this reason, in our planned study, we will investigate the effects of chair-based exercise training in COPD patients in acute exacerbation. There is no study in the literature investigating the effects of chair-based exercise training in COPD patients in acute exacerbation. For this reason, our study will provide important information support to the literature.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who were hospitalized due to acute exacerbation of COPD

Exclusion criteria

  • Patients with orthopedic or neurological problems that may interfere with assessment and education,
  • Uncooperative patients,
  • Patients with advanced heart problems such as acute coronary syndrome, stable angina pectoris, severe arrhythmias (Atrial fibrillation etc.), decompensated heart failure.

Treatment and study plan

Treatment group, Chair-Based Exercise Training

Other

The weights of the elastic bands to be used in the exercises will be determined by the physiotherapist according to the abilities and development of the participants.

The intensity of the exercise will be adjusted according to the dyspnea or fatigue patients feel according to the Modified Borg Scale.

During the exercises, heart rate and oxygen saturation will be measured with a pulse oximeter, and blood pressure will be measured with a sphygmomanometer.

Chair-based exercise training will be applied to the patients every day they are hospitalized.

Control group, Breathing exercise

Other

Breathing exercise will be applied to the patients every day they are hospitalized.

Primary outcomes

  1. Functional Exercise Capacity

    Time frame: Seven day

    Functional exercise capacity will be evaluated with 6-minute walk test.

  2. Pulmonary Function Test

    Time frame: Seven day

    This test was evaluated using a spirometry by which is evaluated dynamic lung functions expressed as percentages of expected values.

Secondary outcomes

  1. Dyspnea

    Time frame: Seven day

    The severity of dyspnea during daily living activities is evaluated using the Modified Medical Research Council (MMRC) dyspnea scale.

  2. One Minute Sit to Stand Test

    Time frame: Seven day

    The number of completed sit to stand repetitions in 1 minute. Patients stand/sit from a chair as many times as they can in one minute.

  3. Timed Up and Go Test

    Time frame: Seven day

    The Timed Up and Go test is evaluated dynamic balance.

  4. Depression and Anxiety

    Time frame: Seven day

    Evaluated using Hospital Anxiety and Depression Scale (Turkish versions of all scales)

  5. Life of quality

    Time frame: Seven day

    Saint George's Respiratory Questionnaire (SGRQ) (Turkish versions of all scales) is used to assess the quality of life of COPD patients.

Sponsors and collaborators

Lead sponsor

Necmettin Erbakan University

Other

Registry information

Official study title

Comparison of the Effects of Chair-Based Exercise Training on Respiratory Functions, Exercise Capacity and Quality of Life in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Oct 3, 2022
Registry last updated
Feb 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.