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OpenTrials
Completed

NCT Number: NCT05504993

Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency.

METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

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Key information

Conditions

Chronic Obstructive Lung Disease Acute Exacerbation of COPD Chronic Disease Comorbidities and Coexisting Conditions Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara University Faculty of Medicine

Ankara, Turkey (Türkiye)

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • COPD patients
  • Admitted to the ward for AECOPD

Exclusion criteria

  • Not giving informed consent
  • Unable to perform PFT
  • Lost to follow-up

Treatment and study plan

Frequency of AECOPD

Other

No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Primary outcomes

  1. Frequency of AECOPD

    Time frame: 1 year

    Frequency of AECOPD in the last one year

Secondary outcomes

  1. Having at least one severe AECOPD

    Time frame: 1 year

    having at least one severe AECOPD in the last year

  2. Frequency of AECOPD for the next one year

    Time frame: 1 year

    the number of AECOPD for 1 year period from the preceding admission, regardless of severity

Sponsors and collaborators

Lead sponsor

Ankara University

Other

Registry information

Important dates

Study start
2018
Primary completion
2018
Study completion
2022
First posted
Aug 17, 2022
Registry last updated
Aug 17, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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