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Completed

NCT Number: NCT00754390

Effects of Calcium and Phytate on Zinc Absorption

This study is determine the effects of dietary calcium and phytate on zinc absorption.

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Key information

Conditions

Dietary Zinc Absorption

Age range

21 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

United States Department of Agriculture Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58202, United States

About this study

Zinc absorption is tested from 2 days of consuming each of four diets with zinc-65 isotope, followed by retention monitoring in a whole body scintillation counter for 4 weeks. All four 4 experimental diets are tested with each subject, in randomized order, for a total of 16 weeks.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Average weight for height

Exclusion criteria

  • Medications other than birth control pills or hormone replacement therapy,
  • Pregnancy within last 6 months

Treatment and study plan

Moderate Calcium, Low phytate Diet

Dietary Supplement

Participants consumed diet containing 700 milligrams calcium and 440 milligrams of phytate for 4 weeks

Moderate Calcium, High Phytate Diet

Dietary Supplement

Participants consumed diet containing 700 milligrams calcium and 1800 milligrams of phytate for 4 weeks

High Calcium, Low Phytate Diet

Dietary Supplement

Participants consumed diet containing 1900 milligrams calcium and 440 milligrams of phytate for 4 weeks

High Calcium, High Phytate Diet

Dietary Supplement

Participants consumed diet containing 1900 milligrams calcium and 1800 milligrams of phytate for 4 weeks

Primary outcomes

  1. Zinc Absorption

    Time frame: 16 weeks

    Retention of Zinc-65 was monitored for 28 days by whole body scintillation counting. The percentage of Zinc-65 absorbed was estimated from the y-intercept of the linear portion of a semilogarithmic retention plot of percent Zinc-65 retained versus time

Sponsors and collaborators

Lead sponsor

USDA Grand Forks Human Nutrition Research Center

Fed

Registry information

Important dates

Study start
2005
Primary completion
2006
Study completion
2006
First posted
Sep 18, 2008
Registry last updated
Jul 2, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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