Skip to main content
OpenTrials
Completed

NCT Number: NCT05269251

Effects of Brachial Plexus Block on Tissue Oxygenation

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Demet Coskun

Ankara, Turkey (Türkiye)

About this study

It has been reported that vasodilation after peripheral nerve blocks increases tissue oxygenation and increases arterial circulation on the ipsilateral side . Near Infrared Spectroscopy (NIRS), a noninvasive measurement method of tissue oxygen level, is used to measure regional hemoglobin oxygen saturation of arterial, venous and capillary blood .

Many studies have compared the effects of upper extremity peripheral nerve blocks on the onset, quality, extent, and postoperative pain of sensory and motor block through axillary, infraclavicular, supraclavicular and interscalene approaches.

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA I-III patients
  • Patients between the ages of 18 and 65
  • Patients who applied axillary block
  • Patients who applied infraclavicular block
  • Patients who applied interscalene block

Exclusion criteria

  • Peripheral nerve disease a history
  • History of thrombosis in the extremity to be blocked
  • History of embolism in the extremity to be blocked
  • Presence of neuropathy

Treatment and study plan

Near Infrared Spectroscopy (NIRS)

Device

After the brachial plexus block, the regional oxygen saturation (rSO2) was monitored for 30 minutes with the Regional Oximetry System (O3™, Masimo, Irvine, CA) and the radial artery diameter with ultrasound in the same period.

Other names: Regional Oximetry System (O3™, Masimo, Irvine, CA)

Primary outcomes

  1. tissue oxygenation

    Time frame: 30 minutes

    Measured from both extremities by Near Infrared Spectroscopy for 30 min after brachial nerve block.

Secondary outcomes

  1. Radial artery diameter

    Time frame: 30 minutes

    measured on the side of the block after brachial nerve block

Sponsors and collaborators

Lead sponsor

Gazi University

Other

Registry information

Official study title

Effects of Brachial Plexus Block Applied With Different Approaches on Tissue Oxygenation

Acronym: BrachialPlexus

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Mar 7, 2022
Registry last updated
Mar 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.