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NCT Number: NCT07408245

Effects of Biocidin on Oral Biofilms

The primary purpose of this study is to evaluate the effects of Biocidin liquid on oral biofilms among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of two weeks of supplementation with label dosing of Biocidin liquid on oral biofilms as assessed by SimplyPERIO (Spectrum Solutions, Salt Lake City, UT).

Recruiting

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Key information

Conditions

Biofilm

Age range

25 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

OvationLab

Richmond, Virginia, 23220, United States

Location status: Recruiting

Location contact

Chris D'Adamo, Ph.D.

CONTACT

[email protected]

‪(240) 232-2103‬

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult females or males age ≥ 25 years
  • Ability to read and speak English
  • Willingness to take use oral Biocidin as directed for two weeks
  • Willingness not to change any other oral health practices for two weeks
  • Willingness not to change dietary habits for two weeks
  • Willingness to perform a SimplyPERIO oral microbiome test before and after the two-week Biocidin intervention

Exclusion criteria

  • Current use of oral Biocidin or botanical mouthwash
  • Use of antibiotics within the past 30 days
  • Current use of fixed intraoral orthodontic appliances (e.g., dental braces, fixed retainers, or similar devices)
  • Known allergies to any of the ingredients in the product
  • Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
  • Participants unable to provide consent

Treatment and study plan

Biocidin Liquid

Dietary Supplement

Broad-spectrum botanical liquid formula

Primary outcomes

  1. Oral Biofilm Microorganisms

    Time frame: Measured at baseline and conclusion of 2-week study

    SimplyPERIO - Oral biofilm microorganism test results are categorized as "low", "medium", and "high".

Study contacts

Contact information is provided by the study sponsor or research team.

Chris D'Adamo, Ph.D.

CONTACT

[email protected]

‪(240) 232-2103‬

Sponsors and collaborators

Lead sponsor

OvationLab

Network

Registry information

Official study title

Prospective Human Study Evaluating the Effects of Biocidin Liquid on Oral Biofilms: An Open-label Pilot Study

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Feb 13, 2026
Registry last updated
Mar 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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