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Completed

NCT Number: NCT05704608

Effects of Aerobic Training Program On Liver Functions

The liver plays a central role in energy exchange, protein synthesis as well as the elimination of waste products from the body. The optimal functioning of the liver is essential for athletic performance. It becomes necessary to maintain the enzymes of the liver at an optimal level so that liver cells can be protected from inflammation or damage. This paper investigated the effects of a twelve-week aerobic exercise program on the liver function of adult athletes. A total of thirty (30) healthy male athletes aged 21 to 24 were recruited for this study and kept in two equal groups. The control group was kept under rigorous supervision and did not participate in any special activities. The experiment group was well-versed in their assigned training program and solely performed the experimental procedure for twelve (12) weeks. Evaluation of all patients in both experimental and control groups was carried out before and after the treatment program by measuring the levels of (Alkaline phosphate, AST/SGOT, ALT/SGPT, Bilirubin Total/indirect/direct, Albumin, Globulin, and Total protein) respectively using standard methods by collecting blood samples, 5 mls each of baseline into lithium heparin containers for estimation of above biochemical parameters at the pathology laboratory accredited by National Accreditation Board for Testing and Calibration Laboratories accredited (NABL, India).

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Key information

Conditions

Liver Functions Behavior Digestive System Diseases Fatty Liver Liver Diseases Motor Activity

Age range

21 year–24 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

King Saud University

Riyadh, 11433, Saudi Arabia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male
  • Age: 21-24 years
  • Healthy
  • Athletes

Exclusion criteria

  • history of severe illness,
  • surgery, or damage to liver,
  • fatty liver disease,
  • cirrhosis,
  • blood infections,
  • neuromuscular illnesses,
  • or the presence of any disorders such as fever, high blood pressure, high blood sugar

Treatment and study plan

Aerobic training

Other

Exercises on a treadmill at different speeds and inclination were performed.

Primary outcomes

  1. Bilirubin-Total

    Time frame: 12 weeks.

    Blood level of Bilirubin-Total was measured.

  2. Serum aspartate aminotransferase/serum glutamic-oxaloacetic transaminase (AST/SGOT)

    Time frame: 12 weeks.

    Blood level of Serum AST/SGOT was measured.

  3. Serum alanine transaminase/Serum Glutamic Pyruvic Transaminase (ALT/SGPT)

    Time frame: 12 weeks.

    Blood level of Serum ALT/SGPT was measured.

  4. Alkaline Phosphatase

    Time frame: 12 weeks.

    Blood level of Alkaline Phosphatase was measured.

  5. Protein-Total

    Time frame: 12 weeks.

    Blood level of Protein-Total was measured.

  6. Albumin

    Time frame: 12 weeks.

    Blood level of Albumin was measured.

  7. Globulin

    Time frame: 12 weeks.

    Blood level of Globulin was measured.

Sponsors and collaborators

Lead sponsor

King Saud University

Other

Registry information

Official study title

Effects of an Aerobic Training Program on Liver Functions in Male Athletes - a Randomized Controlled Trial

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jan 30, 2023
Registry last updated
Jan 30, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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